Novartis to Acquire Avidity Biosciences in $12 Billion Deal

Oct 26, 2025

Novartis, a global pharmaceutical company based in Switzerland, has agreed to buy Avidity Biosciences, a U.S. biotechnology firm, for $72 per share in cash. The total value of the deal is about $12 billion.
Avidity Biosciences is recognized for its innovation in RNA therapeutics, especially its Antibody Oligonucleotide Conjugates (AOCs™) platform. This acquisition will add three late-stage neuroscience programs to Novartis’s pipeline, focusing on genetic neuromuscular diseases.
Before the completion of the acquisition, Avidity will separate its early-stage precision cardiology programs into a new, publicly traded company named SpinCo.
The acquisition is expected to close in the first half of 2026, as long as SpinCo is successfully separated and other standard closing requirements are met. Novartis anticipates that this deal will support new product launches by 2030 and improve its sales growth outlook.

What is Avidity Biosciences known for?

Avidity Biosciences develops a new class of medicines called Antibody Oligonucleotide Conjugates (AOCs™), mainly focused on treating genetic neuromuscular diseases.

Why is Novartis buying Avidity Biosciences?

Novartis wants to strengthen its neuroscience division and bring new therapies to its pipeline, especially in genetic neuromuscular diseases.

What will happen to Avidity’s other projects?

Avidity's early-stage cardiology research will be placed into a new publicly traded company called SpinCo before the acquisition is completed.

When will the deal be completed?

The deal is expected to close in the first half of 2026, after all conditions are met.

Sources
Novartis nears $70-plus per share deal to acquire Avidity Biosciences, Bloomberg...
Reuters
Swiss drugmaker Novartis AG is close to acquiring U.S. biotech Avidity Biosciences for over $70 per share, Bloomberg News reported on Sunday, citing a person familiar with the matter.
Novartis is in talks to buy U.S. biotech firm Avidity Biosciences for more than...
CNBC
Swiss pharmaceutical giant Novartis is nearing a deal to buy biotechnology company Avidity Biosciences for more than $70 a share, Bloomberg News reported.
Novartis agrees to acquire Avidity Biosciences, an innovator in RNA therapeutics...
GlobeNewsWire
Ad hoc announcement pursuant to Art. 53 LR Transaction strengthens neuroscience franchise for Novartis with three late-stage programs that address genetic neuromuscular diseases Advances the Novartis xRNA strategy by adding a scientifically robust, muscle-directed, Antibody Oligonucleotide Conjugate...
Novartis to acquire Avidity Biosciences for $12 billion
Reuters
Swiss drugmaker Novartis on Sunday said it agreed to acquire Avidity Biosciences for $12 billion.
Avidity Biosciences Enters into Agreement to be Acquired by Novartis AG
PRNewsWire
Novartis to acquire Avidity for USD 72.00 per share in cash for total equity value of approximately USD 12.0 billion  Avidity expects to separate its early-stage precision cardiology programs into a new company ("SpinCo") Closing expected in 1H2026 subject to completion of the separation of SpinCo f...
Novartis Deal Values Avidity Biosciences At $12 Billion
Barrons
The acquisition would raise the 2024-2029 expected sales compound annual growth rate for Novartis to 6% from 5%, it said.
Novartis to acquire Avidity Biosciences for about $12B
New York Post
Novartis has been proactively striking deals this year to address the impending patent cliff for some of its blockbuster drugs, including Entresto for heart failure, Xolair for asthma and Cosentyx for autoimmune diseases.
Novartis Agrees to Acquire Avidity Biosciences for $12 Billion
WSJ
The Swiss pharmaceutical company says the purchase would complement its existing pipeline of treatments for neuromuscle disorders.
Novartis Agrees $12 Billion Biotech Deal for Avidity
Bloomberg Markets and Finance
Novartis agreed to buy biotechnology company Avidity in a deal valued at $12 billion, making it the Swiss drugmaker's biggest acquisition in more than a decade and adding several potential blockbuster treatments as generic competition looms for its current top-sellers. Sam Fazeli of Bloomberg Intell...
Novartis shares slip, Avidity soars after $12 billion biotech deal
Reuters
Shares of Novartis fell 1% on Monday following news of the company's plans to acquire U.S. biotech Avidity Biosciences for about $12 billion, marking the Swiss drugmaker's largest acquisition under CEO Vas Narasimhan.
Trump's trade deals, Novartis acquires Avidity, Taco Bell's beverage push and mo...
CNBC
President Donald Trump penned several trade agreements ahead of his expected meeting with China leader Xi Jinping later this week. Novartis announced it will buy Avidity Biosciences.
Novartis to acquire Avidity Biosciences in $12B deal
Proactive Investors
Novartis AG (ADR) (NYSE:NVS) announced it will acquire San Diego-based biopharmaceutical firm Avidity Biosciences (NASDAQ:RNA), which is developing RNA therapeutics for genetic neuromuscular diseases, in a transaction valued at approximately US$12 billion. The deal, unanimously approved by the board...
Is it too late to buy Avidity stock after Novartis deal?
Invezz
Novartis (NYSE: NVS) revealed plans of acquiring Avidity Biosciences Inc (NASDAQ: RNA) in a $12 billion all-cash transaction – valuing each share of the biotech company at $72 on Monday. The announcement sent RNA shares soaring roughly 44% in a single session – indicating investor enthusiasm and con...
Why Avidity Biosciences And Dyne Therapeutics Stocks Soared 40% Monday
Investopedia
Shares of Avidity Biosciences (RNA) soared more than 40% Monday after Novartis (NVS) agreed to buy the U.S. biopharmaceutical firm for about $12 billion in cash to expand its RNA-based disease-fighting pipeline.
Avidity Biosciences Soars After $72 Per Share Novartis Takeover
Benzinga
Avidity Biosciences, Inc. (NASDAQ:RNA) stock surged after announcing a $12 billion all-cash acquisition by Novartis AG (NYSE:NVS), marking one of the largest biotech buyouts of the year.
$HAREHOLDER ALERT: The M&A Class Action Firm Announces An Investigation of Avidi...
PRNewsWire
NEW YORK , Oct. 27, 2025 /PRNewswire/ -- Class Action Attorney Juan Monteverde with Monteverde & Associates PC (the "M&A Class Action Firm"), has recovered millions of dollars for shareholders and is recognized as a Top 50 Firm in the 2024 ISS Securities Class Action Services Report. The firm is hea...
Why Avidity Biosciences Stock Blasted 42% Higher Today
The Motley Fool
It is being acquired for quite a meaty premium. The buyer is a top name in the global pharmaceuticals space.
Avidity Biosciences Investor Alert By The Former Attorney General Of Louisiana:...
Business Wire
NEW YORK & NEW ORLEANS--(BUSINESS WIRE)--Former Attorney General of Louisiana Charles C. Foti, Jr., Esq. and the law firm of Kahn Swick & Foti, LLC (“KSF”) are investigating the proposed sale of Avidity Biosciences, Inc. (NasdaqGM: RNA) to Novartis AG. Under the terms of the proposed transaction, sh...
Novartis CEO says pharma giant has the firepower for big M&A deals: 'Can never b...
CNBC
The Swiss drugmaker announced its biggest deal in a decade on Sunday, as its set to buy Avidity Biosciences for about $12 billion.  "We have adequate firepower to do deals like this and to bolster the growth profile of the company," the CEO told CNBC.
RNA Stock Alert: Halper Sadeh LLC Is Investigating Whether the Sale of Avidity B...
Business Wire
NEW YORK--(BUSINESS WIRE)--Halper Sadeh LLC, an investor rights law firm, is investigating whether the sale of Avidity Biosciences, Inc. (NASDAQ: RNA) to Novartis for $72.00 per share in cash is fair to Avidity shareholders. Halper Sadeh encourages Avidity shareholders to click here to learn more ab...
Novartis CEO: We're never done with M&A
CNBC International TV
Vas Narasimhan, CEO of pharmaceuticals company, Novartis, discusses the company's latest $12 billion acquisition of Avidity Biosciences, and ongoing negotiations with the U.S. administration over potential pharmaceutical tariffs. ----- Subscribe: @CNBCInternationalLive Subscribe to CNBC Internationa...
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