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Avacta Group PLC
Avacta Group Plc engages in the provision of Affimer reagents for licensing into third-party research and diagnostic products, and creates new Affimer medicines for development in-house and licensing to large pharmaceutical companies. The company is headquartered in Wetherby, West Yorkshire. The company went IPO on 2003-09-08. The firm is focused on developing cancer immunotherapies and diagnostics based on its Affimer and prelCISION platforms. The company has two divisions: Therapeutics and Diagnostics. Avacta’s therapeutics division develops cancer immunotherapies combining its platforms: Affimer biotherapeutics and prelCISION tumor targeted chemotherapy. The Affimer platform is a class of biotherapeutic based on a naturally occurring human protein. Avacta's prelCISION targeted chemotherapy platform releases active chemotherapy in the tumor, which limits the systemic exposure that causes damage to healthy tissues, and thereby improves the overall safety and therapeutic potential of these anti-cancer treatments. Avacta’s diagnostics division utilizes its Affimer platform to develop diagnostics and works with partners world-wide to develop Affimer reagents with the objective of establishing royalty-bearing license deals.
Avacta Group Plc engages in the provision of Affimer reagents for licensing into third-party research and diagnostic products, and creates new Affimer medicines for development in-house and licensing to large pharmaceutical companies. The company is headquartered in Wetherby, West Yorkshire. The company went IPO on 2003-09-08. The firm is focused on developing cancer immunotherapies and diagnostics based on its Affimer and prelCISION platforms. The company has two divisions: Therapeutics and Diagnostics. Avacta’s therapeutics division develops cancer immunotherapies combining its platforms: Affimer biotherapeutics and prelCISION tumor targeted chemotherapy. The Affimer platform is a class of biotherapeutic based on a naturally occurring human protein. Avacta's prelCISION targeted chemotherapy platform releases active chemotherapy in the tumor, which limits the systemic exposure that causes damage to healthy tissues, and thereby improves the overall safety and therapeutic potential of these anti-cancer treatments. Avacta’s diagnostics division utilizes its Affimer platform to develop diagnostics and works with partners world-wide to develop Affimer reagents with the objective of establishing royalty-bearing license deals.
Clinical Progress: Avacta's lead program faridoxorubicin (FAP-Dox/AVA6000) advanced to Phase Ib expansion, with pivotal data expected late 2025 and further updates at ESMO in October.
Second Program Milestone: FAP-exatecan (AVA6103) remains on track to dose its first patient in Q1 2026, with encouraging preclinical data showing durable responses.
Financial Position: Cash at period end was GBP 12.65 million, with a cash runway extending into Q1 2026. Recent proceeds from asset sales and equity raises have supported operations and bond payments.
Funding & Partnerships: Management is focused on securing partnerships to fund further development, prioritizing non-dilutive deals and keeping full ownership of FAP-exatecan until clinical data emerges.
Strategic Outlook: Multiple commercial opportunities, industry interest, and a strong IP position underpin confidence in the pre|CISION platform's potential.
Shareholder Engagement: Commitment to improved communications with regular investor updates around data releases and direct engagement events.
