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Atea Pharmaceuticals Inc
NASDAQ:AVIR

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Atea Pharmaceuticals Inc Logo
Atea Pharmaceuticals Inc
NASDAQ:AVIR
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Price: 5.67 USD -2.91% Market Closed
Market Cap: $451.7m

Atea Pharmaceuticals Inc
Investor Relations

Atea Pharmaceuticals, Inc. is a clinical stage company, which focuses on discovering, developing, and commercializing antiviral therapeutics. The company is headquartered in Boston, Massachusetts and currently employs 59 full-time employees. The company went IPO on 2020-10-30. The firm is focused on discovering, developing, and commercializing antiviral therapeutics to enhance the lives of patients suffering from life-threatening viral infections. The firm is engaged in the development of product candidates to treat COVID-19, hepatitis C virus (HCV), dengue and respiratory syncytial virus (RSV). The firm is developing bemnifosbuvir (AT-527), which is an investigational, novel, orally administered guanosine nucleotide analog polymerase inhibitor for the treatment of COVID-19. The company is developing bemnifosbuvir and ruzasvir, an investigational nonstructural protein 5A (NS5A) inhibitor for the treatment of chronic HCV infection. The firm is also developing AT-752, an oral, purine nucleotide prodrug for the treatment of dengue. AT-527 is designed to inhibit viral replication by interfering with viral RNA polymerase.

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Last Earnings Call
Fiscal Period
Q4 2025
Call Date
Mar 5, 2026
AI Summary
Q4 2025

Phase III timing: Top-line readout expected for C-BEYOND midyear 2026 and for C-FORWARD by year-end 2026.

Clinical progress: Global Phase III program is fully enrolled in North America (>880 patients in C-BEYOND) and expected to enroll >1,760 patients combined; Phase III trials are randomized, active-controlled and powered 90% with a 5% noninferiority margin.

Regimen profile: Bemnifosbuvir + ruzasvir demonstrated strong Phase II results (98% SVR12 in the protocol treatment population; 95% SVR12 in the efficacy-evaluable/MITT-type analyses) and a differentiated profile: short 8-week duration for noncirrhotics, low drug–drug interaction risk, no food effect and no dose adjustment for hepatic/renal impairment.

New program: AT-587 selected as lead for HEV; IND/CTA-enabling work underway with first-in-human study anticipated midyear 2026 and PoC by year-end 2026; company estimates HEV market opportunity of $750 million–$1 billion in U.S./Europe.

Commercial prep: Company expects a focused U.S. launch with ~75 commercial hires, blister packaging for adherence, and market research indicating high prescriber interest (physicians said they'd likely use the regimen in ~50% of their patients).

Balance sheet & runway: Cash, cash equivalents and marketable securities were $301.8 million at December 31, 2025; management projects the cash runway extends to 2027. The company returned $25 million to shareholders via share repurchases in 2025.

Key Financials
Cash, cash equivalents and marketable securities
$301.8 million
C-BEYOND enrollment (North America)
more than 880 patients
Combined Phase III expected enrollment
more than 1,760 patients
Phase II SVR12 (protocol treatment population)
98% SVR12
Phase II SVR12 (efficacy-evaluable / MITT)
95% SVR12
Statistical powering of Phase III trials
powered 90% with 5% noninferiority margin
U.S. new chronic HCV infections (annual reported)
160,000 new chronic infections
Patients treated annually in U.S.
85,000 treated annually
U.S. HCV net sales (approx)
$1.3 billion
Estimated people in U.S. with hepatitis C
approximately 4 million people
Projected liver cancer incidence
from approximately 850,000 cases in 2025 to 1.4 million (projected over next 5 years)
Commercial field organization size
around 75 people
Share repurchase in 2025
$25 million
Estimated HEV market opportunity (U.S./Europe)
$750 million to $1 billion per year
Earnings Call Recording
Other Earnings Calls

Management

Dr. Jean-Pierre Sommadossi Ph.D.
Founder, Chairman, CEO & President
No Bio Available
Ms. Andrea J. Corcoran J.D.
CFO, Executive VP of Legal & Secretary
No Bio Available
Mr. Wayne Foster CPA
Executive VP of Finance & Chief Accounting Officer
No Bio Available
Dr. Janet M. J. Hammond M.D., Ph.D.
Chief Development Officer
No Bio Available
Dr. Maria Arantxa Horga M.D.
Chief Medical Officer
No Bio Available
Ms. Jonae R. Barnes
Senior Vice President of Investor Relations & Corporate Communications
No Bio Available
Mr. Ariyapadi N. Krishnaraj
Vice President of Marketing
No Bio Available
Mr. Adel Moussa Ph.D.
Executive Vice President of Chemistry
No Bio Available
Mr. Xiao-Jian Zhou Ph.D.
Executive Vice President of Early Stage Development
No Bio Available
Mr. John F. Vavricka
Chief Commercial Officer
No Bio Available

Contacts

Address
MASSACHUSETTS
Boston
125 Summer Street, 16Th Floor
Contacts
+18572048109.0
ateapharma.com
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