Fennec Pharmaceuticals Inc
NASDAQ:FENC
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Fennec Pharmaceuticals Inc
Fennec Pharmaceuticals, Inc. operates as a biopharmaceutical company. The company is headquartered in Durham, North Carolina and currently employs 10 full-time employees. The company went IPO on 2001-06-05. The firm is focused on the development of PEDMARK for the prevention of platinum-induced ototoxicity in pediatric cancer patients. The Company’s only product candidate in the clinical-stage of development is PEDMARK. The company announced two results of Phase III clinical trials for the prevention of cisplatin induced hearing loss, or ototoxicity in children, including the pivotal Phase III study SIOPEL 6 and the proof-of-concept Phase III study in collaboration with the Children’s Oncology Group (COG ACCL0431). PEDMARK has the potential to reduce the incidence and/or grade of chemotherapy-induced hearing loss. The Company’s four subsidiaries includes Oxiquant, Inc. and Fennec Pharmaceuticals, Inc., both Delaware corporations, Cadherin Biomedical Inc., a Canadian company, and Fennec Pharmaceuticals (EU) Limited (Fennec Limited), an Ireland company. Apart from Fennec Pharmaceuticals, Inc., all subsidiaries are inactive.
Fennec Pharmaceuticals, Inc. operates as a biopharmaceutical company. The company is headquartered in Durham, North Carolina and currently employs 10 full-time employees. The company went IPO on 2001-06-05. The firm is focused on the development of PEDMARK for the prevention of platinum-induced ototoxicity in pediatric cancer patients. The Company’s only product candidate in the clinical-stage of development is PEDMARK. The company announced two results of Phase III clinical trials for the prevention of cisplatin induced hearing loss, or ototoxicity in children, including the pivotal Phase III study SIOPEL 6 and the proof-of-concept Phase III study in collaboration with the Children’s Oncology Group (COG ACCL0431). PEDMARK has the potential to reduce the incidence and/or grade of chemotherapy-induced hearing loss. The Company’s four subsidiaries includes Oxiquant, Inc. and Fennec Pharmaceuticals, Inc., both Delaware corporations, Cadherin Biomedical Inc., a Canadian company, and Fennec Pharmaceuticals (EU) Limited (Fennec Limited), an Ireland company. Apart from Fennec Pharmaceuticals, Inc., all subsidiaries are inactive.
Revenue Growth: Fennec posted $9.7 million in net product sales for Q2 2025, up 33% year-over-year and 10% quarter-over-quarter, matching its highest quarterly net sales ever.
Commercial Momentum: The company reported its third consecutive quarter of sequential revenue growth, driven by both new customer acquisition and retention of existing accounts, with 14 new accounts added in Q2.
PEDMARK Adoption: PEDMARK continues to gain traction, including formulary addition by a major national oncology provider group and positive peer-reviewed guidance from NCODA, supporting efforts to make PEDMARK the standard of care.
Operating Expenses: Cash operating expenses were approximately $11 million for the quarter, with expectations that expenses will decrease in the second half of 2025, keeping full-year cash OpEx in line with 2024 at around $33 million.
European Expansion: The EU launch of PEDMARQSI by partner Norgine is underway in the UK and Germany, with broader rollouts and milestone payments expected as pricing is finalized and new countries come online.
Japan Opportunity: Results from the Japanese trial are anticipated in Q4, with Fennec planning for regulatory submission and potential partnership, targeting a market about one-third the size of the US/EU pediatric opportunity.