Vaxcyte Inc
NASDAQ:PCVX

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Vaxcyte Inc
NASDAQ:PCVX
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Price: 46.46 USD 0.69% Market Closed
Market Cap: 6.1B USD

Vaxcyte Inc
Investor Relations

Vaxcyte Inc. has carved a niche in the biotechnology industry with its focus on developing next-generation vaccines to tackle some of the most challenging infectious diseases. The company, headquartered in San Carlos, California, leverages its proprietary cell-free protein synthesis platform, XpressCF™, which enables the rapid production of complex proteins at scale. This technology forms the backbone of its vaccine development process, allowing Vaxcyte to bypass traditional cell-based methods that can be both time-consuming and costly. At the core of Vaxcyte's mission is its commitment to addressing unmet medical needs by enhancing the efficacy and safety profiles of vaccines, ultimately aiming to deliver superior alternatives to existing products on the market.

Vaxcyte's business model is built on a strategic blend of research and development, partnerships, and intellectual property. The company invests heavily in R&D to advance its pipeline of vaccine candidates, with a particular emphasis on conjugate vaccines targeting bacterial infections such as pneumococcal diseases. Revenue generation is primarily driven through collaborations and licensing agreements with larger pharmaceutical companies that provide upfront payments, milestones, and potential royalties. These partnerships not only validate Vaxcyte’s scientific approach but also furnish the essential capital to sustain its innovative programs and bring its cutting-edge vaccines to market. As Vaxcyte continues to make strides in vaccine development, the company positions itself as a key player in the quest for more effective disease prevention solutions.

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Last Earnings Call
Fiscal Period
Q4 2024
Call Date
Feb 25, 2025
AI Summary
Q4 2024

Strong Cash Position: Vaxcyte ended 2024 with $3.13 billion in cash, cash equivalents, and investments, supporting its development and manufacturing plans.

VAX-31 Adult Data: VAX-31 showed robust clinical results in adults, exceeding or meeting non-inferiority criteria for all shared serotypes with PCV20 and achieving higher immune responses for many.

Upcoming Milestones: The company expects top-line VAX-24 infant Phase II immunization data by the end of Q1 2025, with VAX-31 infant data expected in mid-2026.

Manufacturing Scale-Up: The build-out of a dedicated manufacturing facility with Lonza is on track for completion by early 2025, preparing for commercial launches.

R&D and G&A Expenses Rising: Substantial increases in R&D and G&A spending are expected in 2025 to support launches, manufacturing, and clinical programs.

Regulatory Progress: VAX-31 received FDA breakthrough therapy designation for adults, potentially expediting its regulatory pathway.

Broad Support for Vaccines: Management reports bipartisan policy support for vaccination and ongoing engagement with regulatory and public health bodies.

Key Financials
Cash, cash equivalents and investments
$3.13 billion
Capital and facility expenditures (2024)
$127.8 million
Total project capital and facility expenditures (to-date)
$214.3 million
Net proceeds from equity offerings (2024)
$2.2 billion
VAX-24 infant Phase II study enrollment
802 participants
Earnings Call Recording
Other Earnings Calls
2024
2023
2022
2021
2020

Management

Mr. Grant E. Pickering M.B.A.
Co-Founder, CEO & Director
No Bio Available
Mr. Andrew L. Guggenhime M.B.A.
President & CFO
No Bio Available
Mr. James Wassil M.B.A., M.S.
Executive VP & COO
No Bio Available
Dr. Ashish Khanna M.B.A., Ph.D.
Co-Founder
No Bio Available
Dr. Jeff Fairman Ph.D.
Co-Founder & VP of Research
No Bio Available
Ms. Elvia Cowan
Senior VP of Finance & Principal Accounting Officer
No Bio Available
Ms. Janet Graesser
Senior Vice President of Corporate Communications & Investor Relations
No Bio Available
Ms. Whitney Jones
Chief People Officer
No Bio Available
Mr. Paul W. Sauer M.B.A.
Senior Vice President of Process Development & Manufacturing
No Bio Available
Mr. Harp Dhaliwal M.B.A.
Senior Vice President of Commercial Manufacturing & Supply Chain
No Bio Available

Contacts

Address
CALIFORNIA
San Carlos
825 Industrial Road, Ste. 300
Contacts
+16508370111.0
vaxcyte.com