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Alnylam Pharmaceuticals Inc
NASDAQ:ALNY

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Alnylam Pharmaceuticals Inc
NASDAQ:ALNY
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Price: 303.96 USD -3.13%
Market Cap: $40.3B

EV/EBITDA

71.4
Current
206%
Cheaper
vs 3-y average of -67.2

Enterprise Value to EBITDA (EV/EBITDA) ratio compares a company`s total enterprise value to its earnings before interest, taxes, depreciation, and amortization. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBITDA
71.4
=
Enterprise Value
$41.8B
/
EBITDA
$557.2m

Enterprise Value to EBITDA (EV/EBITDA) ratio compares a company`s total enterprise value to its earnings before interest, taxes, depreciation, and amortization. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBITDA
71.4
=
Enterprise Value
$41.8B
/
EBITDA
$557.2m

Valuation Scenarios

Alnylam Pharmaceuticals Inc is trading above its industry average

If EV/EBITDA returns to its Industry Average (13.3), the stock would be worth $56.59 (81% downside from current price).

Statistics
Positive Scenarios
0/2
Maximum Downside
-81%
Maximum Upside
No Upside Scenarios
Average Downside
81%
Scenario EV/EBITDA Value Implied Price Upside/Downside
Current Multiple 71.4 $303.96
0%
Industry Average 13.3 $56.59
-81%
Country Average 14.4 $61.08
-80%

Forward EV/EBITDA
Today’s price vs future ebitda

Today's Enterprise Value EBITDA Forward EV/EBITDA
$41.8B
/
Jan 2026
$557.2m
=
71.4
Current
$41.8B
/
Dec 2026
$1.3B
=
32
Forward
$41.8B
/
Dec 2027
$2.2B
=
19.4
Forward
$41.8B
/
Dec 2028
$2.4B
=
17.5
Forward

Forward EV/EBITDA shows whether today’s EV/EBITDA still looks high or low once future ebitda are taken into account.

Peer Comparison

All Multiples
EV/EBITDA
P/E
All Countries
Close
Market Cap EV/EBITDA P/E
US
Alnylam Pharmaceuticals Inc
NASDAQ:ALNY
41.5B USD 71.4 128.2
FR
Pharnext SCA
OTC:PNEXF
6T USD -194 446.1 -160 127.7
US
Abbvie Inc
NYSE:ABBV
355.3B USD 14 83.7
US
Amgen Inc
NASDAQ:AMGN
187.9B USD 14.1 24.2
US
Gilead Sciences Inc
NASDAQ:GILD
165.8B USD 11.9 19
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
110.5B USD 20.8 27.8
US
Epizyme Inc
F:EPE
94.1B EUR -581 -533.6
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
81B USD 13 17.5
NL
argenx SE
XBRU:ARGX
41.2B EUR 40.2 37.3
US
Seagen Inc
F:SGT
39.3B EUR -66.6 -61.8
AU
CSL Ltd
ASX:CSL
62.2B AUD 10.5 30.9
EV/EBITDA Multiple
EBITDA Growth EV/EBITDA to Growth
US
Alnylam Pharmaceuticals Inc
NASDAQ:ALNY
Average EV/EBITDA: 24.5
71.4
62%
1.2
FR
Pharnext SCA
OTC:PNEXF
Negative Multiple: -194 446.1 N/A N/A
US
Abbvie Inc
NYSE:ABBV
14
12%
1.2
US
Amgen Inc
NASDAQ:AMGN
14.1
10%
1.4
US
Gilead Sciences Inc
NASDAQ:GILD
11.9
9%
1.3
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
20.8
18%
1.2
US
E
Epizyme Inc
F:EPE
Negative Multiple: -581 N/A N/A
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
13
17%
0.8
NL
argenx SE
XBRU:ARGX
40.2
49%
0.8
US
S
Seagen Inc
F:SGT
Negative Multiple: -66.6 N/A N/A
AU
CSL Ltd
ASX:CSL
10.5
7%
1.5
P/E Multiple
Earnings Growth PEG
US
Alnylam Pharmaceuticals Inc
NASDAQ:ALNY
Average P/E: 46.1
128.2
79%
1.6
FR
Pharnext SCA
OTC:PNEXF
Negative Multiple: -160 127.7 N/A N/A
US
Abbvie Inc
NYSE:ABBV
83.7
97%
0.9
US
Amgen Inc
NASDAQ:AMGN
24.2
20%
1.2
US
Gilead Sciences Inc
NASDAQ:GILD
19
16%
1.2
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
27.8
19%
1.5
US
E
Epizyme Inc
F:EPE
Negative Multiple: -533.6 N/A N/A
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
17.5
14%
1.3
NL
argenx SE
XBRU:ARGX
37.3
30%
1.2
US
S
Seagen Inc
F:SGT
Negative Multiple: -61.8 N/A N/A
AU
CSL Ltd
ASX:CSL
30.9
9%
3.4

Market Distribution

Higher than 89% of companies in the United States of America
Percentile
89th
Based on 9 875 companies
89th percentile
71.4
Low
0 — 10
Typical Range
10 — 21.5
High
21.5 —
Distribution Statistics
the United States of America
Min 0
30th Percentile 10
Median 14.4
70th Percentile 21.5
Max 1 767 274.1

Alnylam Pharmaceuticals Inc
Glance View

In the heart of the biotechnology revolution, Alnylam Pharmaceuticals Inc. has been a pioneering force, transforming the landscape of medicine through its innovative use of RNA interference (RNAi) technology. Founded in 2002 and based in Cambridge, Massachusetts, the company set out on a bold mission to silence disease-causing genes by targeting RNA, the intermediary that carries genetic instructions necessary for protein synthesis. This groundbreaking approach diverges from traditional methods that focus on targeting proteins directly and instead intervenes earlier in the disease process to eliminate or reduce the proteins before they can wreak havoc on the body. Fueled by extensive research and a robust pipeline, Alnylam has successfully brought several RNAi-based therapies to market, such as Onpattro and Givlaari, which address rare genetic disorders with high unmet medical needs. Alnylam's business model is centered around the commercial success of its novel therapies, partnerships with other pharmaceutical giants, and strategic collaborations for global distribution. By securing alliances with industry leaders like Sanofi and Regeneron, Alnylam has been able to expand its research capabilities and broaden its market reach. Revenue for the company is primarily driven by the sales of its approved products, which continue to grow as they gain acceptance within the medical community. Additionally, Alnylam's extensive patent portfolio and its strategic licensing agreements provide an additional revenue stream, safeguarding its innovations and ensuring it retains a competitive edge in this rapidly advancing field. Through its relentless pursuit of innovation, Alnylam continues to position itself as a trailblazer in turning the once theoretical promise of RNAi into a clinical reality.

ALNY Intrinsic Value
149.48 USD
Overvaluation 51%
Intrinsic Value
Price $303.96
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