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Apellis Pharmaceuticals Inc
NASDAQ:APLS

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Apellis Pharmaceuticals Inc
NASDAQ:APLS
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Price: 40.94 USD Market Closed
Market Cap: $5.2B

EV/S

5.1
Current
14%
Cheaper
vs 3-y average of 5.9

Enterprise Value to Sales (EV/S) ratio compares a company`s total enterprise value to its revenue. It shows how much investors are paying for each dollar of the company`s sales, including both equity and debt.

EV/S
5.1
=
Enterprise Value
$5B
/
Revenue
$1B

Enterprise Value to Sales (EV/S) ratio compares a company`s total enterprise value to its revenue. It shows how much investors are paying for each dollar of the company`s sales, including both equity and debt.

EV/S
5.1
=
Enterprise Value
$5B
/
Revenue
$1B

Valuation Scenarios

Apellis Pharmaceuticals Inc is trading below its 3-year average

If EV/S returns to its 3-Year Average (5.9), the stock would be worth $47.48 (16% upside from current price).

Statistics
Positive Scenarios
3/4
Maximum Downside
-40%
Maximum Upside
+180%
Average Upside
45%
Scenario EV/S Value Implied Price Upside/Downside
Current Multiple 5.1 $40.94
0%
3-Year Average 5.9 $47.48
+16%
5-Year Average 14.2 $114.6
+180%
Industry Average 6.2 $50.29
+23%
Country Average 3 $24.62
-40%

Forward EV/S
Today’s price vs future revenue

Today's Enterprise Value Revenue Forward EV/S
$5B
/
Jan 2026
$1B
=
5.1
Current
$5B
/
Dec 2026
$882.5m
=
5.7
Forward
$5B
/
Dec 2027
$1B
=
4.8
Forward
$5B
/
Dec 2028
$1.2B
=
4.2
Forward
$5B
/
Dec 2029
$1.4B
=
3.6
Forward
$5B
/
Dec 2030
$1.6B
=
3.2
Forward
$5B
/
Dec 2031
$1.7B
=
3
Forward
$5B
/
Dec 2032
$1.8B
=
2.8
Forward
$5B
/
Dec 2033
$1.9B
=
2.6
Forward

Forward EV/S shows whether today’s EV/S still looks high or low once future revenue are taken into account.

Peer Comparison

All Multiples
EV/S
P/E
All Countries
Close
Market Cap EV/S P/E
US
Apellis Pharmaceuticals Inc
NASDAQ:APLS
5.2B USD 5.1 231.5
FR
Pharnext SCA
OTC:PNEXF
6T USD 33 691 034.4 -160 127.7
US
Abbvie Inc
NYSE:ABBV
351.3B USD 6.7 83.9
US
Amgen Inc
NASDAQ:AMGN
185.7B USD 6.2 24.1
US
Gilead Sciences Inc
NASDAQ:GILD
161.8B USD 5.9 19
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
109.3B USD 8.4 27.6
US
Epizyme Inc
F:EPE
94.1B EUR 2 092.7 -533.6
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
79.4B USD 4 17.6
NL
argenx SE
XBRU:ARGX
41.2B EUR 10.5 37.3
US
Seagen Inc
F:SGT
39.3B EUR 19.6 -61.8
AU
CSL Ltd
ASX:CSL
62.7B AUD 3.4 30.7
P/E Multiple
Earnings Growth PEG
US
Apellis Pharmaceuticals Inc
NASDAQ:APLS
Average P/E: 59
231.5
68%
3.4
FR
Pharnext SCA
OTC:PNEXF
Negative Multiple: -160 127.7 N/A N/A
US
Abbvie Inc
NYSE:ABBV
83.9
97%
0.9
US
Amgen Inc
NASDAQ:AMGN
24.1
20%
1.2
US
Gilead Sciences Inc
NASDAQ:GILD
19
16%
1.2
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
27.6
19%
1.5
US
E
Epizyme Inc
F:EPE
Negative Multiple: -533.6 N/A N/A
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
17.6
14%
1.3
NL
argenx SE
XBRU:ARGX
37.3
30%
1.2
US
S
Seagen Inc
F:SGT
Negative Multiple: -61.8 N/A N/A
AU
CSL Ltd
ASX:CSL
30.7
9%
3.4

Market Distribution

In line with most companies in the United States of America
Percentile
68th
Based on 11 256 companies
68th percentile
5.1
Low
0 — 1.6
Typical Range
1.6 — 5.3
High
5.3 —
Distribution Statistics
the United States of America
Min 0
30th Percentile 1.6
Median 3
70th Percentile 5.3
Max 4 613 320.1

Apellis Pharmaceuticals Inc
Glance View

In the realm of biotechnology, Apellis Pharmaceuticals Inc. has carved out a niche by pioneering therapies that target the complement system, an integral part of the immune response. Founded in 2009, the company quickly honed in on the inhibition of C3, a protein central to the activation of the complement cascade, which can drive various diseases when dysregulated. Through its proprietary platform, Apellis has developed novel therapeutic candidates that aim to modulate the immune system from an entirely fresh angle. The company focuses on addressing serious medical conditions that currently have limited treatment options, such as age-related macular degeneration (AMD) and paroxysmal nocturnal hemoglobinuria (PNH), by employing targeted therapies to reduce inflammation and improve patient outcomes. Apellis’s business strategy revolves around a model that not only aims to bring innovative treatments to market but also to establish partnerships that broaden the reach of its technology. The company's flagship drug, Empaveli, received FDA approval for PNH in 2021 and underscores its potential to capture larger market segments within rare disease treatment areas. By investing heavily in research and development, Apellis seeks to expand its pipeline while also collaborating with other firms to enhance its capabilities and share the risks and rewards associated with drug development. Revenue is generated primarily through sales of its approved therapies, as well as milestone payments and royalties from partnerships, setting Apellis on a path poised for growth if it continues to advance its clinical programs successfully.

APLS Intrinsic Value
40.58 USD
Overvaluation 1%
Intrinsic Value
Price $40.94
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