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Clene Inc.
NASDAQ:CLNN

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Clene Inc.
NASDAQ:CLNN
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Price: 6.57 USD 3.96% Market Closed
Market Cap: $77.4m

EV/EBITDA

-4
Current
119%
More Expensive
vs 3-y average of -1.8

Enterprise Value to EBITDA (EV/EBITDA) ratio compares a company`s total enterprise value to its earnings before interest, taxes, depreciation, and amortization. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBITDA
-4
=
Enterprise Value
$70.8m
/
EBITDA
$-21.6m

Enterprise Value to EBITDA (EV/EBITDA) ratio compares a company`s total enterprise value to its earnings before interest, taxes, depreciation, and amortization. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBITDA
-4
=
Enterprise Value
$70.8m
/
EBITDA
$-21.6m

Valuation Scenarios

Clene Inc. is trading above its industry average

If EV/EBITDA returns to its Industry Average (13.3), the stock would be worth $-22 (435% downside from current price).

Statistics
Positive Scenarios
0/2
Maximum Downside
-461%
Maximum Upside
No Upside Scenarios
Average Downside
448%
Scenario EV/EBITDA Value Implied Price Upside/Downside
Current Multiple -4 $6.57
0%
Industry Average 13.3 $-22
-435%
Country Average 14.4 $-23.74
-461%

Forward EV/EBITDA
Today’s price vs future ebitda

Today's Enterprise Value EBITDA Forward EV/EBITDA
$70.8m
/
Jan 2026
$-21.6m
=
-4
Current
$70.8m
/
Dec 2026
$-25.7m
=
-2.8
Forward
$70.8m
/
Dec 2027
$-32.3m
=
-2.2
Forward
$70.8m
/
Dec 2028
$3.3m
=
21.4
Forward

Forward EV/EBITDA shows whether today’s EV/EBITDA still looks high or low once future ebitda are taken into account.

Peer Comparison

All Multiples
EV/EBITDA
P/E
All Countries
Close
Market Cap EV/EBITDA P/E
US
Clene Inc.
NASDAQ:CLNN
71.3m USD -4 -2.7
FR
Pharnext SCA
OTC:PNEXF
6T USD -194 446.1 -160 127.7
US
Abbvie Inc
NYSE:ABBV
354.5B USD 14.1 84.7
US
Amgen Inc
NASDAQ:AMGN
186.5B USD 14 24.2
US
Gilead Sciences Inc
NASDAQ:GILD
164.9B USD 12.2 19.4
US
Epizyme Inc
F:EPE
94.1B EUR -581 -533.6
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
111.2B USD 21.1 28.1
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
78.9B USD 13 17.5
NL
argenx SE
XBRU:ARGX
42B EUR 41 38
AU
CSL Ltd
ASX:CSL
62.3B AUD 10.3 30.2
US
Seagen Inc
F:SGT
39.3B EUR -66.6 -61.8
EV/EBITDA Multiple
EBITDA Growth EV/EBITDA to Growth
US
Clene Inc.
NASDAQ:CLNN
Average EV/EBITDA: 18
Negative Multiple: -4
N/A N/A
FR
Pharnext SCA
OTC:PNEXF
Negative Multiple: -194 446.1 N/A N/A
US
Abbvie Inc
NYSE:ABBV
14.1
12%
1.2
US
Amgen Inc
NASDAQ:AMGN
14
10%
1.4
US
Gilead Sciences Inc
NASDAQ:GILD
12.2
9%
1.4
US
E
Epizyme Inc
F:EPE
Negative Multiple: -581 N/A N/A
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
21.1
18%
1.2
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
13
17%
0.8
NL
argenx SE
XBRU:ARGX
41
49%
0.8
AU
CSL Ltd
ASX:CSL
10.3
7%
1.5
US
S
Seagen Inc
F:SGT
Negative Multiple: -66.6 N/A N/A
P/E Multiple
Earnings Growth PEG
US
Clene Inc.
NASDAQ:CLNN
Average P/E: 34.6
Negative Multiple: -2.7
N/A N/A
FR
Pharnext SCA
OTC:PNEXF
Negative Multiple: -160 127.7 N/A N/A
US
Abbvie Inc
NYSE:ABBV
84.7
97%
0.9
US
Amgen Inc
NASDAQ:AMGN
24.2
20%
1.2
US
Gilead Sciences Inc
NASDAQ:GILD
19.4
16%
1.2
US
E
Epizyme Inc
F:EPE
Negative Multiple: -533.6 N/A N/A
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
28.1
19%
1.5
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
17.5
14%
1.3
NL
argenx SE
XBRU:ARGX
38
30%
1.3
AU
CSL Ltd
ASX:CSL
30.2
9%
3.4
US
S
Seagen Inc
F:SGT
Negative Multiple: -61.8 N/A N/A

Market Distribution

Lower than 100% of companies in the United States of America
Percentile
0th
Based on 9 875 companies
0th percentile
-4
Low
0 — 10
Typical Range
10 — 21.5
High
21.5 —
Distribution Statistics
the United States of America
Min 0
30th Percentile 10
Median 14.4
70th Percentile 21.5
Max 1 767 274.1

Clene Inc.
Glance View

Market Cap
77.4m USD
Industry
Biotechnology

Clene, Inc. is a clinical-stage biopharmaceutical company, which focuses on the development of therapeutics for neurodegenerative diseases. The company is headquartered in Salt Lake City, Utah and currently employs 95 full-time employees. The company went IPO on 2018-08-27. The firm is focused on the treatment of neurodegenerative disease with potential first-in-class nanotherapeutics to treat energetic failure and neurological diseases. The Company’s lead drug candidate, CNM-Au8, is an oral suspension of gold nanocrystals that drive critical cellular energetic metabolism in the central nervous system (CNS). CNM-Au8 increases energy production and utilization to accelerate neurorepair and improve neuroprotection. CNM-Au8 is being evaluated in a Phase III registration trial in amyotrophic lateral sclerosis (ALS) and a Phase II trial for the treatment of chronic optic neuropathy in patients with stable relapsing multiple sclerosis (MS). The firm has also advanced into the clinic an aqueous solution of ionic zinc and silver for anti-viral and anti-microbial uses.

CLNN Intrinsic Value
9.64 USD
Undervaluation 32%
Intrinsic Value
Price $6.57
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