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Gyre Therapeutics Inc
NASDAQ:GYRE

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Gyre Therapeutics Inc
NASDAQ:GYRE
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Price: 7.44 USD Market Closed
Market Cap: $679.3m

EV/EBITDA

44.9
Current
6%
More Expensive
vs 3-y average of 42.4

Enterprise Value to EBITDA (EV/EBITDA) ratio compares a company`s total enterprise value to its earnings before interest, taxes, depreciation, and amortization. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBITDA
44.9
=
Enterprise Value
$597.7m
/
EBITDA
$14m

Enterprise Value to EBITDA (EV/EBITDA) ratio compares a company`s total enterprise value to its earnings before interest, taxes, depreciation, and amortization. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBITDA
44.9
=
Enterprise Value
$597.7m
/
EBITDA
$14m

Valuation Scenarios

Gyre Therapeutics Inc is trading above its 3-year average

If EV/EBITDA returns to its 3-Year Average (42.4), the stock would be worth $7.03 (6% downside from current price).

Statistics
Positive Scenarios
0/4
Maximum Downside
-99%
Maximum Upside
No Upside Scenarios
Average Downside
61%
Scenario EV/EBITDA Value Implied Price Upside/Downside
Current Multiple 44.9 $7.44
0%
3-Year Average 42.4 $7.03
-6%
5-Year Average 0.3 $0.05
-99%
Industry Average 13.3 $2.21
-70%
Country Average 14.4 $2.38
-68%

Forward EV/EBITDA
Today’s price vs future ebitda

Today's Enterprise Value EBITDA Forward EV/EBITDA
$597.7m
/
Jan 2026
$14m
=
44.9
Current
$597.7m
/
Dec 2026
$-18.9m
=
-31.7
Forward
$597.7m
/
Dec 2027
$-23.5m
=
-25.5
Forward

Forward EV/EBITDA shows whether today’s EV/EBITDA still looks high or low once future ebitda are taken into account.

Peer Comparison

All Multiples
EV/EBITDA
P/E
All Countries
Close
Market Cap EV/EBITDA P/E
US
Gyre Therapeutics Inc
NASDAQ:GYRE
679.4m USD 44.9 135.1
FR
Pharnext SCA
OTC:PNEXF
6T USD -194 446.1 -160 127.7
US
Abbvie Inc
NYSE:ABBV
351.3B USD 14 83.9
US
Amgen Inc
NASDAQ:AMGN
185.7B USD 14 24.1
US
Gilead Sciences Inc
NASDAQ:GILD
161.8B USD 11.9 19
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
109.3B USD 20.7 27.6
US
Epizyme Inc
F:EPE
94.1B EUR -581 -533.6
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
79.4B USD 13.1 17.6
NL
argenx SE
XBRU:ARGX
41.2B EUR 40.2 37.3
US
Seagen Inc
F:SGT
39.3B EUR -66.6 -61.8
AU
CSL Ltd
ASX:CSL
62.7B AUD 10.5 30.7
EV/EBITDA Multiple
EBITDA Growth EV/EBITDA to Growth
US
Gyre Therapeutics Inc
NASDAQ:GYRE
Average EV/EBITDA: 21.2
44.9
N/A N/A
FR
Pharnext SCA
OTC:PNEXF
Negative Multiple: -194 446.1 N/A N/A
US
Abbvie Inc
NYSE:ABBV
14
12%
1.2
US
Amgen Inc
NASDAQ:AMGN
14
10%
1.4
US
Gilead Sciences Inc
NASDAQ:GILD
11.9
9%
1.3
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
20.7
18%
1.2
US
E
Epizyme Inc
F:EPE
Negative Multiple: -581 N/A N/A
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
13.1
17%
0.8
NL
argenx SE
XBRU:ARGX
40.2
49%
0.8
US
S
Seagen Inc
F:SGT
Negative Multiple: -66.6 N/A N/A
AU
CSL Ltd
ASX:CSL
10.5
7%
1.5
P/E Multiple
Earnings Growth PEG
US
Gyre Therapeutics Inc
NASDAQ:GYRE
Average P/E: 46.9
135.1
230%
0.6
FR
Pharnext SCA
OTC:PNEXF
Negative Multiple: -160 127.7 N/A N/A
US
Abbvie Inc
NYSE:ABBV
83.9
97%
0.9
US
Amgen Inc
NASDAQ:AMGN
24.1
20%
1.2
US
Gilead Sciences Inc
NASDAQ:GILD
19
16%
1.2
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
27.6
19%
1.5
US
E
Epizyme Inc
F:EPE
Negative Multiple: -533.6 N/A N/A
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
17.6
14%
1.3
NL
argenx SE
XBRU:ARGX
37.3
30%
1.2
US
S
Seagen Inc
F:SGT
Negative Multiple: -61.8 N/A N/A
AU
CSL Ltd
ASX:CSL
30.7
9%
3.4

Market Distribution

Higher than 85% of companies in the United States of America
Percentile
85th
Based on 9 875 companies
85th percentile
44.9
Low
0 — 10
Typical Range
10 — 21.5
High
21.5 —
Distribution Statistics
the United States of America
Min 0
30th Percentile 10
Median 14.4
70th Percentile 21.5
Max 1 767 274.1

Gyre Therapeutics Inc
Glance View

Gyre Therapeutics Inc is a US-based company operating in Biotechnology industry. The company is headquartered in San Diego, California and currently employs 7 full-time employees. The company went IPO on 2006-04-12. Gyre Therapeutics, Inc., formerly Catalyst Biosciences, Inc., is a biotechnology company. The firm is focused on organ fibrosis and inflammatory diseases. The firm is primarily focused on the development and commercialization of Hydronidone (F351) for the treatment of Metabolic Dysfunction Associated Steatohepatitis (MASH-associated liver fibrosis (MASH fibrosis). The firm is also advancing a diverse pipeline in China through a controlling interest in Beijing Continent, including pirfenidone, F573, F528, and F230. Pirfenidone is used for idiopathic pulmonary fibrosis and is undergoing Phase 3 trials in dermatomyositis interstitial lung disease, systemic sclerosis-associated interstitial lung disease, and pneumoconiosis, along with a Phase 1 trial in diabetic kidney disease. F573 is being investigated for acute-on-chronic liver failure, while F528 and F230 are being evaluated for chronic obstructive pulmonary disease and pulmonary arterial hypertension, respectively.

GYRE Intrinsic Value
26.81 USD
Undervaluation 72%
Intrinsic Value
Price $7.44
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