Standard BioTools Inc
NASDAQ:LAB

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Standard BioTools Inc
NASDAQ:LAB
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Price: 0.9224 USD 2.66% Market Closed
Market Cap: $359.8m

Q1-2025 Earnings Call

AI Summary
Earnings Call on May 6, 2025

Revenue: Q1 2025 revenue was $40.8 million, down 10% year-over-year and in line with expectations.

Guidance Maintained: Full year 2025 revenue guidance remains unchanged at $165 million to $175 million, with revenue expected to be weighted more toward the second half of the year.

Cost Reductions: Non-GAAP operating expenses decreased by 22% year-over-year, driven by $10 million in additional cost reductions this quarter, bringing total annualized savings since the SomaLogic merger to $90 million.

Gross Margin: Non-GAAP gross margin was 53.2%, down from 56.2% last year, mainly due to lower volumes and product mix.

Cash Position: Ended Q1 with $261 million in cash and equivalents and no material debt, with significantly reduced cash burn versus last year.

Instrument Sales: Instrument revenue grew 24% year-over-year in Q1, led by continued success of the Hyperion XTi platform.

Academic Headwinds: Mid-teens percentage decline expected in Americas academic revenue, with ongoing academic funding delays and spending curbs.

M&A Focus: Management confirms a disciplined M&A approach, noting a robust pipeline of potential deals but high standards for execution.

Revenue Performance

Q1 2025 revenue was $40.8 million, down 10% year-over-year and in line with internal plans. The decline was attributed to a tough market backdrop and a strong prior-year quarter due to elevated backlog, especially in lab services. Consumables and service revenue were softer, while instruments showed growth.

Guidance & Outlook

Full year 2025 revenue guidance remains at $165 million to $175 million. Management expects performance to be weighted toward the back half of the year, driven by larger projects in the pipeline rather than typical seasonality. Persistent headwinds, especially in Americas academia, are reflected in guidance.

Cost Control & Profitability

Cost reduction efforts remain a priority. Non-GAAP operating expenses fell by 22% year-over-year, with $10 million of additional annualized cost reductions in Q1, totaling $90 million since the SomaLogic merger. Adjusted EBITDA loss also improved by 29% versus last year. Management reiterates a focus on reaching adjusted EBITDA positive in 2026.

Product Mix & Demand Trends

Instrument sales were strong in Q1, up 24% year-over-year, especially for the Hyperion XTi spatial imaging systems. Consumables and lab services were down, with consumables revenue declining 16% year-over-year. Delays and funding pressures in U.S. academia affected demand, while biopharma and international markets showed resilience.

Academic & Biopharma Markets

Americas academia remains a challenging segment, with a mid-teens percentage revenue decline expected for the year. Funding delays and spending curbs have led to both delayed and uncertain purchases in instruments and consumables. In contrast, biopharmaceutical customer demand is healthy, with a growing funnel beyond historical major accounts.

Tariffs & Macro Impact

New tariff measures are adding complexity but are considered manageable. The estimated gross annualized impact is in the low single-digit millions of dollars and falls within existing guidance. The company is selectively passing through some of these costs to customers, and management is closely monitoring operational impacts.

Product Innovation & Partnerships

Recent product launches included new consumables (Single SOMAmer Reagents), instruments (CyTOF XT PRO), and assays (SomaScan 3.7K Select). The partnership with Illumina is seen as a long-term growth driver, with moderate revenue contribution expected for 2025 and stronger impact anticipated from 2026 onward.

M&A and Strategic Direction

Management remains committed to a disciplined M&A approach, targeting four to six deals by 2026. While the market offers more opportunities due to current conditions, the bar for acquisitions remains high. The company continues to leverage operational synergies and value creation from recent M&A activities.

Revenue
$40.8 million
Change: Down 10% year-over-year.
Guidance: $165 million to $175 million in 2025.
Consumables Revenue
$14.5 million
Change: Down 16% year-over-year.
Instruments Revenue
$7.8 million
Change: Up 24% year-over-year.
Services Revenue
$17.6 million
Change: Down 16% year-over-year.
Gross Margin
53.2%
Change: Down from 56.2% last year.
Operating Expenses
$38.6 million
Change: Down 22% year-over-year.
Net Loss
$26 million
Change: Improved by $6.2 million or 19% year-over-year.
Adjusted EBITDA
-$16.9 million
Change: Improved by $6.8 million or 29% year-over-year.
Cash and Equivalents
$261 million
No Additional Information
Total Cash Burn
$34 million
Change: Down from $101 million in prior year quarter.
Adjusted Cash Burn
$31 million
Change: Down 33% from $47 million in prior year quarter.
Revenue
$40.8 million
Change: Down 10% year-over-year.
Guidance: $165 million to $175 million in 2025.
Consumables Revenue
$14.5 million
Change: Down 16% year-over-year.
Instruments Revenue
$7.8 million
Change: Up 24% year-over-year.
Services Revenue
$17.6 million
Change: Down 16% year-over-year.
Gross Margin
53.2%
Change: Down from 56.2% last year.
Operating Expenses
$38.6 million
Change: Down 22% year-over-year.
Net Loss
$26 million
Change: Improved by $6.2 million or 19% year-over-year.
Adjusted EBITDA
-$16.9 million
Change: Improved by $6.8 million or 29% year-over-year.
Cash and Equivalents
$261 million
No Additional Information
Total Cash Burn
$34 million
Change: Down from $101 million in prior year quarter.
Adjusted Cash Burn
$31 million
Change: Down 33% from $47 million in prior year quarter.

Earnings Call Transcript

Transcript
from 0
Operator

Good day, and welcome to the Standard BioTools Inc. First Quarter 2025 Financial Results Conference Call. [Operator Instructions] Please note, this event is being recorded.

I would now like to turn the conference over to John Graziano, Vice President of Investor Relations. Please go ahead.

J
John Graziano
executive

Thank you, operator, and good afternoon, everyone. Welcome to Standard BioTools First Quarter 2025 Earnings Conference Call. Leading the call today is Michael Egholm, President and Chief Executive Officer; and Alex Kim, Chief Financial Officer.

At the close of market today, Standard BioTools released its financial results for the quarter ended March 31, 2025. During this call, we will review our results and provide an update on our financial and operational performance, 2025 outlook, market trends and strategic initiatives.

During the call, we'll make forward-looking statements about events and circumstances that have not yet occurred, including plans and projections for our business, our outlook for 2025 and future financial results, market trends and opportunities, the impacts of tariffs and funding pressures and our expectations related to the combined operations with SomaLogic, including potential synergies and our business outlook for the combined company. These statements are subject to substantial risks and uncertainties that may cause actual events or results to differ materially from current expectations.

For information regarding other related risks, see the Risk Factors section of the company's annual report on Form 10-K filed with the SEC on March 11, 2025, and in the company's other filings with the SEC. The forward-looking statements on this call are based on information currently available to us, and we disclaim any obligation to update these statements, except as may be required by law.

During the call, we will also present some financial information on a non-GAAP basis. We believe these non-GAAP financial measures are useful in evaluating our core performance and as a baseline for assessing the future earnings potential of the company. We use these non-GAAP measures in our own evaluation of continuing operating performance. We encourage you to carefully consider our results on a GAAP and non-GAAP basis. The reconciliation between non-GAAP measures and their GAAP equivalents are provided in the tables accompanying today's press release and as an appendix to today's presentation slides.

Please note that management will be referring to a slide presentation, including updated supplemental financial information within the webcast today. Following prepared remarks, we will host a Q&A session. Today's slide presentation, along with a replay of the webcast will be available on the Investors section of our website. I would like to now turn the call over to Michael Egholm, President and CEO of Standard BioTools.

M
Michael Egholm
executive

Thank you, John. Good afternoon, everyone, and welcome to Standard BioTools First Quarter 2025 Earnings Call. Joining me today is Alex Kim, our Chief Financial Officer.

Before we begin, I want to thank our customers, employees and investors. Your support is what fuels our work and drives our mission to set a new standard in life sciences, empower researchers, accelerating discovery, all while delivering long-term value to our shareholders. Standard BioTools delivered a solid first quarter with results on plan and in line despite a choppy operating backdrop.

Execution continues to improve as we build rigor across the organization, guided by lean principles through our Standard BioTools Business System, or just SBS. As operators, we are staying grounded in fundamentals, focusing on what we can control, managing with precision and driving towards profitability.

Before diving into the details, it's worth stepping back for a moment. While the broader environment remains dynamic, we are navigating it from a position of strength with a diversified portfolio, a disciplined operating model, healthy balance sheet and a team that's getting sharper quarter after quarter as forecast accuracy improves and consistency in how we run the business grows.

We are particularly pleased with our strategic foothold in proteomics and a series of recent high-impact product launches. Last week at the American Association of Cancer Research annual meeting, or AACR, we announced a new SomaScan offering that will pair well with the highly anticipated distributed NGS-based Illumina partnered solution. Together, these advancements expand our reach and push the boundaries of what's possible in translational and clinical research.

From the outside, the macro backdrop may still cloud the picture, but inside, we are strong. Our diversified business in Life Sciences allows us to operate multiple levers to navigate the waters, including a patient and disciplined M&A strategy, which is benefiting from a growing number of compelling assets and opportunities.

With that, let's turn to the numbers. In Q1, while not growth, we executed to plan and delivered $40.8 million in revenue. This was down 10% year-over-year as the market got worse against last year's Q1, and we had elevated backlog to start 2024. Despite this and not enough to wave the all-clear flag, we have seen encouraging traction in capital expenditures with strength in our instrument business, which also helped by a favorable year-over-year comp. Consumables and service revenue, which represents larger portions of the mix, particularly in the Americas, was softer than usual and still exhibits variability quarter-to-quarter. That said, when you zoom out at multi-quarter trend, you see a pattern of improving precision, sharpened commercial execution and more consistency, which gives us confidence in the direction we are heading.

While headwinds remain and in some cases, with NIH budgets and tariff concerns intensified, our diversification continues to serve us well. International markets and biopharma engagement remain more resilient, and we are seeing continued traction across those segments. The impact is reflected in our previously announced guidance, which assume a mid-teens percentage decline in Americas academic revenue of roughly high single-digit million dollars at the midpoint.

On the impact of new tariff measures, while they have added a layer of complexity and disruption to global trade are from our perspective, manageable. While not material to near-term financials, including the top line, we are actively accessing the operational impact and working across teams to mitigate risk and maintain flexibility. In some cases, we are passing costs through to customers. In others, we are absorbing it but selectively. If fully absorbed, we estimate the impact on gross margin and adjusted EBITDA would be in the low single-digit millions within the bounds of our current outlook and consistent with what we communicated during our last quarterly update.

Specifically, products manufactured in Canada and shipped to the U.S.A. falls under the U.S. MCA and are currently excluded from tariffs. Products made in Singapore and shipped to the U.S., primarily our Biomark instruments and IFC consumables are now subject to a 10% tariff. SomaScan kits made in the U.S. and shipped to authorized sites in China, an area of growth, though smaller portion of the revenue today are subject to significant tariffs.

For the full year, there is no change to our prior guidance. We continue to expect full year 2025 revenue in the range of $165 million to $175 million. We're taking a measured approach, modeling persistent headwinds, though anticipating back half seasonality. With $261 million in cash and equivalents on the balance sheet and no material debt, we remain well capitalized and disciplined in our resource allocation.

Our healthy cash position is a key asset and differentiator in this environment, and we intend to protect it, accordingly. Our eyes remain fixed on reaching adjusted EBITDA positive in 2026, all while closely monitoring the backdrop in which we operate today. Being well capitalized is only part of the story, and we have taken decisive steps to streamline operations, reduce costs and reinforce our operating leverage.

Non-GAAP OpEx improved 22% year-over-year, operating loss improved 45% and adjusted EBITDA improved 29%. Those results are the output of hard choices made early and implemented swiftly. In January, as previously announced, we executed an additional $10 million in cost reduction on top of the $80 million operationalized in 2024, primarily focused on long horizon R&D projects, moves that enable us today to stay nimble without compromising near-term priorities. We're leaner, more agile and structurally advantaged as we move through 2025.

What's making this level of discipline possible and sustainable is SBS. It's how we run the business. It brings a mindset of continuous improvement to everything we do and accountability to every part of the organization. Nowhere is that more evident than in our integration of SomaLogic. A year ago, it was an obscured diamond, complex, underleveraged and overlooked, but we saw what others could not. In just over 12 months, we applied SBS, took out over $80 million in costs and got the fundamentals right. We leveraged several high impact head-to-head studies to reposition the technology and drive interest, ramped activity with leading biobanks, improved manufacturing, launched new products and importantly, reengaged our key partner, Illumina.

This is a platform now positioned to win in large-scale population studies and drive translational and clinical research. That turnaround didn't happen by chance. It happened because we applied the SBS flywheel and moved with precision. The momentum is building around this uniquely powerful platform, high plex, high precision and now backed by a more focused organization and data. Design speaks for itself. SomaScan is unlocking entirely new possibilities in disease research and drug development like never before, with unmatched scale and precision that legacy antibody-based technologies simply cannot match. We're seeing growing traction across pharma, biobanks and large-scale population studies. And importantly, the data keep reinforcing the value and differentiation of the platform.

Our deep partnership with Illumina is a critical part of this strategy, extending SomaScan's reach to thousands of sequencing labs worldwide and will bring high-throughput proteomics to more researchers than ever before. This momentum was on full display at AACR, where roughly 90 posters and presentations featured our solutions, underscoring the breadth and utility of entire proteomics portfolio and its growing role in translational and clinical research. A couple of examples stood out.

In a prostate cancer analysis conducted by the multicenter EPIC study, SomaScan 7K identified over 50 protein markers, including PSA and many previously unknown markers, while in a comparable analysis, the nearest competitor found just one known biomarker, demonstrating SomaScan's best-in-class coverage and ability to uncover both known and novel biomarkers that have the potential to assess prostate cancer risk up to decades in advance of cancer diagnosis. More is really more in proteomics.

In another study by Daiichi Sankyo and AstraZeneca that stems from multiple Phase II and Phase III clinical trials, SomaScan showed the potential to predict and monitor serious lung complications from cancer treatments. In this case, most commonly antibody drug conjugates or ADCs, detecting early warning signs up to 60 days before symptoms appeared and helping assess patient risk before treatment begins.

At AACR, we also introduced 3 new offerings, spanning consumables, instruments and services. Single SOMAmer Reagents, the CyTOF XT PRO, a higher throughput flow system with Part 11 compliant software for clinical trial researchers and the SomaScan 3.7K Select Assay. Collectively, they complement our category-leading 11K Assay and the Select 3.7K Assay offers more usable content at higher precision than the nearest affinity proteomics competitors' highest throughput offering at improved economics, purpose-built for translational clinical research and aligned with our mission to help pharma make better drugs faster.

Turning to our products. Our revenue mix for the quarter remained balanced across the portfolio, with consumables at 35%, instruments 19% and lab and field services at 30% and 13%, respectively. We saw growth globally from our instrument business, while consumables and lab were soft, in part due to project timing and funding uncertainty in the Americas. Consumables positioned at the top of our product pyramid, were down mid-teens year-over-year and down low single digits sequentially with the largest impact in flow.

To help close that gap, we recently launched the sites of XT PRO, a faster automated system purpose-built to drive pull-through. Early signals from the field have been encouraging. SomaScan authorized sites, which have become a steady contributor to the consumables line, were down modestly year-over-year due to order timing in the U.S., though experiencing increased activity internationally, particularly in APAC.

Looking ahead, we expect additional lift as our distributed solution with Illumina comes online. Consumables remain a strategic priority, high margin, recurring and essential to our model long term. Instruments were a bright spot with double-digit year-over-year growth, led by continued demand for our Hyperion XTi spatial imaging systems. These are high throughput, high-performance systems and importantly, each placement builds installed base leverage for future consumable pull-through.

Spatial proteomics where the Hyperion XTi plays was named 2024 Nature Method of the Year, a strong endorsement from the scientific community, and we're beginning to see that recognition translate into market adoption. Services were down mid-teens year-over-year, driven primarily by a decline in lab services. Beyond the elevated backlog referenced earlier, SomaScan remains concentrated in a handful of large accounts, while less so today, timing and variability is still expected and impacts quarterly performance. U.S. academia also weighed on volume this quarter, though partially offset by increased pharma project activity and modest growth ex U.S.

Big picture, we are focused on making high-precision proteomics more accessible, as we expand distributed offerings through authorized sites and the Illumina partnership, we expect broader adoption and more consistent utilization of our service offering. This is a long-term growth market with solid fundamentals, and we believe we are well positioned to scale with it.

At Standard BioTools, we are building a durable diversified life science tools platform grounded in operations and strategic consolidation. Our mission is to overcome the scale and profitability bottlenecks that have long held this sector back to be the partner of choice for customers and innovators alike. And we're doing it with intention, a portfolio increasingly weighted towards high-margin consumables, disciplined capital deployment and a flywheel that compounds value over time.

With valuations under pressure and innovation accelerating, we are seeing real opportunities to continue to expand. Strategically, we are pursuing a highly disciplined approach, focused on derisked technologies with line of sight to commercialization and value creation, a strong margin profile and clear integration synergies. Every deal runs through the SBS playbook where we strip out inefficiencies, optimize operations and scale with speed. The bar remains high, but the pipeline is full and the opportunity set is compelling. We're playing the long game, and we're doing it with a team of proven operators, a clear strategy and the resources to execute.

With that, I'll turn the call over to Alex. Alex?

H
Hanjoon Kim
executive

Thank you, Michael, and thank you all for joining our call today. I will walk us through our financial results in more detail and provide some additional context for the quarter. Please refer to today's press release and the appendix to our earnings deck for more information, including a reconciliation of GAAP to non-GAAP measures that I will be discussing here.

Also note, we are no longer breaking out our financial results into proteomics and genomics. This reflects our evolving nature of our business, where what we have previously labeled genomics, principally our microfluidics-based integrated fluidic circuits, or IFC chips is increasingly being applied across proteomics, sample preparation and liquid handling applications. We now view our overall business as offering a portfolio of multi-omic tools designed to provide customers with the best solution based on the problem they are trying to solve. We do not operate our day-to-day business as 2 segments. And with our integration activities and operational synergies being realized, we are seeing more and more leverage of our resources across our product lines, including manufacturing, research and development and sales and marketing.

As a result, we believe it's more meaningful to look at our financials as one operating segment. We will, however, continue to break out sales into consumables, instruments, lab services and field services.

So let's start with revenue on Slide 12. Our first quarter revenue came in at $40.8 million. That's down 10% year-over-year and in line with our expectations. As Michael noted, we had a strong first quarter last year as we entered 2024 with an elevated backlog, the majority of which related to our SomaScan lab services business.

Breaking revenue down further, consumables revenue was $14.5 million in the first quarter, down 16% compared to 2024. This was attributed to lower volumes impacted by lower Americas academia revenue as well as fewer large-scale clinical research projects in the quarter. Our SomaScan authorized sites continue to purchase our assay kits. And as we've discussed before, we believe distributed solutions, including our partnership with Illumina, will be a key step forward to establishing market leadership in proteomics.

Expanding our ability to supply more sites globally is highly complementary to our existing lab services business and strengthens our overall market position. Instruments revenue came in at $7.8 million in the first quarter, up 24% year-over-year compared to the first quarter of 2024. This was largely driven by continued sales traction in our spatial proteomics business, particularly the Hyperion XTi, building on the momentum seen exiting 2024.

As our installed base continues to grow, we expect this to drive consumables growth. Services revenue, which includes both lab services and field services was $17.6 million in the first quarter, down 16% year-over-year compared to the first quarter of 2024. Lab services was down 19%, largely due to the previously mentioned gap in backlog. We did see some impact due to project timing and Americas academia funding delays. Field services was down 11% as anticipated on fewer active service contracts as aged legacy instruments go off contract and lower on-demand service and parts revenue on improved quality and uptime of our instruments. This is further evidence of the positive impact that we are having on our customers' experience.

Moving on to gross margins on Slide 13. Our non-GAAP gross margins, which exclude depreciation, amortization and stock-based compensation, was 53.2% in the first quarter of 2025 versus 56.2% in the first quarter of 2024. Our first quarter margins were particularly impacted by lower volume, lower price realization on services and product mix. These masked strong improvements that we saw in operating efficiencies.

Our SBS-driven activities to reduce waste and improve quality are evident across the organization, and we anticipate this to benefit gross margin expansion over the near and long term as volume returns.

Moving on to operating expenses on Slide 14. Our non-GAAP operating expenses, which exclude merger-related costs, stock-based compensation and restructuring charges, were $38.6 million in the first quarter of 2025, a decrease of $10.7 million or down 22% compared to the same period in 2024. Sequentially, from the fourth quarter of 2024, we delivered a 10% reduction.

In the first quarter, we operationalized an additional $10 million in annual run rate cost reductions, as we mentioned on our last call, as we delayed investments in a long-term R&D project. We are now totaling $90 million in annualized cost reductions since the merger with SomaLogic, which is important to reiterate as we navigate through the current macroeconomic uncertainty.

On Slide 15, our net loss in the quarter was $26 million compared to a net loss of $32.2 million in the first quarter of 2024, representing an improvement of $6.2 million or 19%. While adjusted EBITDA for the first quarter of 2025 was a loss of $16.9 million versus an adjusted EBITDA loss of $23.7 million in the first quarter of 2024, an improvement of $6.8 million or 29%.

That brings me to cash on Slide 16. We ended the first quarter with approximately $261 million in cash, cash equivalents, restricted cash and short-term investments with no material debt. Our total cash burn was $34 million in the first quarter of 2025 versus $101 million in the first quarter of 2024. Our adjusted cash burn to support ongoing operations was $31 million in the first quarter of 2025, representing a 33% reduction versus $47 million in the first quarter of 2024.

We are continuing to see material reductions in our cash burn coming through as a result of our restructuring efforts, the ongoing realization of merger cost synergies as well as operational improvements. We believe we are well positioned with our strategic plan and our balance sheet to support the growth of our business towards our profitability targets.

As Michael said, we are not changing our full year revenue guidance of $165 million to $175 million. We continue to expect the year to be back half weighted based on our internal funnel metrics and not on any assumed recovery in the macro dynamics. We continue to expect a mid-teens percentage decline in our Americas academia revenue, a high single-digit millions revenue impact versus 2024. And with respect to our tariffs, our gross annualized impact is estimated to be in the low single-digit millions of dollars to bound our exposure. We plan to pass these tariffs to our customers where possible, be mindful of market conditions and driving volume growth.

Clearly, the geopolitical backdrop is currently highly volatile and stiff macro headwinds persist. However, as we stand here today, looking at the year ahead, we are well positioned, controlling what we can with multiple cost levers to pull on and deploy if needed and a robust balance sheet. We remain committed to delivering long-term profitable revenue growth and increasing shareholder value.

Back to you, Michael.

M
Michael Egholm
executive

Thanks, Alex. We thank you all for your continued support as we navigate these dynamic end markets. We look forward to seeing many of you at upcoming conferences, and stay tuned for details on our upcoming proteomics roundtable series, where we'll dive deeper into the science, strategy and exciting opportunities ahead. And now I hand the call back to the operator for Q&A.

Operator

[Operator Instructions] And our first question today will come from Dan Brennan of TD Cowen.

K
Kyle Boucher
analyst

This is Kyle on for Dan. I wanted to start on the reiterated guide. You said nothing has really changed in your view in terms of the weighting of revenue this year, more back half weighted. Understanding you guys don't guide quarterly, but I think the Street is looking for revenue down a bit Q-over-Q on one of the easiest comps of the year next quarter. That being said, I guess, how should we think about the percentage split between first half, second half?

M
Michael Egholm
executive

I'll let Alex answer that one. And good to hear, Kyle.

H
Hanjoon Kim
executive

Yes. Thanks, Kyle. We're not being overly specific on that. But as we look at our internal funnel, we do see some larger projects that will hit in the back half of the year. So it's less the seasonality that you might have seen in the past, but more driven by our funnel metrics.

K
Kyle Boucher
analyst

Got it. And then maybe on the instrument demand this year. First quarter instrument number looks pretty good relative to our model at least. Anything you can share, I guess, on the funnel? Did you see any pull forward in the first quarter maybe? I guess how are you seeing your overall sales funnel going forward?

M
Michael Egholm
executive

We're really -- we're encouraged by the growth in our funnel, primarily in the Hyperion XTi, but also some traction on our other instruments. And it's really all the good work we did last year in a difficult CapEx environment. So we saw some opening up in the markets at the end of the year. And so we carried that momentum into Q1.

We haven't -- on the instrument side, it's always a little bit hard to say whether it's a pull forward or not, but I can't think of any that was pull forward due to tariffs or other things. It may impact consumables a little bit, but again, not materially. And again, just in this choppy environment, we continue just to focus on control last year when CapEx was tough, we kept focusing on just building the funnel, and we're now seeing some good traction, but not declaring victory yet.

K
Kyle Boucher
analyst

Got it. Maybe if I can sneak in one more here on the M&A side. Earlier this year, you targeted the 4, 6 deals between this year and 2026. Clearly, there have been many change in the market since you initially laid out that goal. And on the call, it sounds like you guys have a pretty good funnel. Has anything changed in regards to your pipeline and the potential timing of any deals?

M
Michael Egholm
executive

Strategic M&A is part of our founding thesis. It remains a core part of the strategy and here. Alex and I are now 4 years into this adventure here, remain ever more convinced that there is a need for consolidator in this space. And I think we have positioned ourselves and we have proven ourselves here. The market needs integration. We see -- we have built the funnel here over the last few years. And what we're seeing now, of course, with the macro and the funding environment and VC investment, it definitely offer up an increased number of opportunities that are actionable now at improved valuation in our point of view.

Having said that, I want to remind everybody that we are highly disciplined. We recognize that our healthy cash position is a key asset, differentiator in this environment. And so we intend to go after that set number of acquisitions here over the next 18 months, but the bar is high.

Operator

And our next question today will come from Matt Stanton of Jefferies.

M
Matthew Stanton
analyst

Maybe one just on U.S. academic and government. You kind of baked a 15% or mid-teens decline in -- on the 4Q call. I think when we caught up then, you had said you hadn't seen any kind of a noticeable change in demand patterns at that time. Now that we've got a bit more time pass and obviously, the news flow there has remained dynamic. But just any more color kind of on how U.S. academic progressed through 1Q and any color on how it's trended here into 2Q? And then within that mid-teens decline for the year, you had baked in prior. Any more color just a finer point in terms of what that bakes in consumables and service versus the instrument piece there?

M
Michael Egholm
executive

Matt, good to hear you. We -- we were like surgical on how we called it out at our last earnings call, and that's the sort of high-level guidance that we made. I just want to remind everybody that we were coming into the year expecting healthy growth in the Americas. So the 15% is still what our mid-teens is still what we're seeing. We have seen -- we've been advised by some institutions that have committed to buying instruments this year that they don't know if they'll be able to do it. We have seen some delay in consumables orders, whether those are permanent, we don't know.

And we have seen at the recent AACR conference, a number of customers from academia could not travel because there were basically curbing all nonessential expenditures. So the sort of broad impact of less fund in U.S. academia definitely holds. I think we've sort of picked it about right from where we are sitting now. And therefore, we are maintaining the guidance.

M
Matthew Stanton
analyst

Okay. That's helpful. And then...

M
Michael Egholm
executive

Maybe -- yes, sorry, I forgot like the little piece of instruments. So we've seen some of the instruments we shipped here were in U.S. academia typically with private funding. We obviously hope NIH's budget will be released and funding will come through for the various grants for all the good stuff we have in the pipeline, I should say.

M
Matthew Stanton
analyst

Great. And then just on the new product side, a handful of new launches last week. Just to focus on the single SOMAmer Reagents. Any kind of early feedback or demand now that you get those out the door? And then can you just remind us on the commercial model there? How much of the existing Soma menu will be available for the single SOMAmer? And then any workflows or customers you expect this to resonate strongly with?

M
Michael Egholm
executive

Yes. So we were in what we call like an early access, a minimal viable products up until now. Now we have made it fully available. We are initially addressing a couple of applications. One is as more and more users or researchers will use SomaScan, they will find a number of -- identify a number of proteins, a very large number, as I just referenced in my script. And one of the first things you will want to do is to do a pull down with those and then analyze by mass spec, confirming post-translational modification, et cetera. So we see that as one avenue.

And then we believe there is a broader reagent market where antibodies are really limited, where we have 11,000 fully synthetic monoclonal reagents binding to human proteins. We believe that's a valuable tool set, and we believe it's a very nice complement to the antibody market. As for how we're going about it, it's a new capability. We have not sold individual reagents before. So I would not have high expectations in the short term. But in the long term, as we're figuring out how to sell this, we see this as a fairly significant opportunity.

Operator

[Operator Instructions] Our next question will come from Paul Knight of KeyBanc.

P
Paul Knight
analyst

Michael, are you expecting the Illumina partnership to generate significant revenue in 2025?

M
Michael Egholm
executive

Paul, we're very excited about the upcoming launch as we talked about at JPM at our last earnings call with the mounting evidence that we are uniquely positioned, the clinical research and insights, most recently at AACR that you can see now Illumina making this available to thousands of labs with sequences. We cautious for '25, but long term, see this as a very strong value driver. Illumina is responsible for the sales, marketing and support, and we are all the fate in the world that they will do a brilliant job. And this is new for them, and this always takes longer than one want. But the outlook is really bright for the technology. And maybe, Alex, you can just comment on what's baked into our '25 assumptions there.

H
Hanjoon Kim
executive

Yes. Maybe just to remind you, in '24, we had some good revenue from Illumina that came through for development to support their development as well as their early access customers. So year-over-year, it will be moderate growth on top of that, but not for many of the reasons Michael mentioned not a significant growth overall. And that is baked into our current guidance. And as Michael mentioned, '26 and beyond, we expect to begin to see strong traction and strong growth there.

P
Paul Knight
analyst

Okay. And then, of course, we can -- I know academic is challenging. But can you talk about what you're seeing within the biopharmaceutical customer set? It does seem like we've started the year with a more visible spending trend there. Are you seeing a better market condition for the major biopharma part of the market?

M
Michael Egholm
executive

Good traction in pharma here in Q1 and have not seen a change from that as I'm sitting here today. Our numbers get a little bit obscured by like historical dependence on a few large customers. As I said in the script, it's becoming ever less so, but it still leads to quarter-to-quarter variation. So underneath that, we're actually seeing a healthy growth and funnel beyond those accounts and in our authorized sites.

P
Paul Knight
analyst

Okay. And then last is the $10 million cost action in early January, should we think about an improved outlook for EBITDA loss this year?

M
Michael Egholm
executive

I'll let Alex handle that.

H
Hanjoon Kim
executive

Yes, slightly. So the action was late January, $10 million annualized. And so yes, you will see that flow through. Our approach, as Michael has said many times, is continuous improvement. And so you'll see us continue to improve our adjusted EBITDA.

Operator

Ladies and gentlemen, at this time, we will conclude our question-and-answer session and also conclude the Standard BioTools conference call. Thank you for attending today's presentation, and you may now disconnect your lines.

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