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Vir Biotechnology Inc
NASDAQ:VIR

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Vir Biotechnology Inc
NASDAQ:VIR
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Price: 8.46 USD 0.71% Market Closed
Market Cap: $1.4B

Vir Biotechnology Inc
Investor Relations

Vir Biotechnology, Inc. operates as a clinical-stage immunology company that focuses on combining immunologic insights with cutting-edge technologies to treat and prevent serious infectious diseases. The company is headquartered in San Francisco, California and currently employs 444 full-time employees. The company went IPO on 2019-10-11. The company has assembled four technology platforms focused on antibodies, T cells, innate immunity, and small interfering ribonucleic acid (siRNA), through internal development, collaborations, and acquisitions. The firm's pipeline consists of sotrovimab and other product candidates targeting COVID-19, hepatitis B virus (HBV), influenza A virus, and human immunodeficiency virus (HIV). Its product candidates include Sotrovimab and VIR-7832, VIR-2218, VIR-3434, VIR-2482, VIR-1111. The company is engaged in developing differentiated monoclonal antibodies (mAbs) as well as vaccines and small molecules that focuses is on treating and preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). VIR-2218 and VIR-3434, are for the treatment of HBV. VIR-2482 is an investigational IM administered influenza A-neutralizing mAb.

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Last Earnings Call
Fiscal Period
Q4 2025
Call Date
Feb 23, 2026
AI Summary
Q4 2025

Strategic Partnership: Vir announced a major global collaboration with Astellas to co-develop and co-commercialize VIR-5500 for prostate cancer, with up to $1.7 billion in upfront and milestone payments.

Positive Phase I Data: VIR-5500 Phase I results showed strong safety and efficacy, with deep and durable PSA responses, and minimal high-grade cytokine release syndrome, even in heavily pretreated patients.

Reduced Costs: Vir reported a 10% reduction in R&D expenses and a 23% reduction in SG&A for 2025 compared to 2024, reflecting ongoing cost discipline.

Financial Strength: Vir ended 2025 with approximately $782 million in cash and expects its cash runway to extend into the second quarter of 2028.

Pipeline Expansion: The Astellas deal enables Vir to accelerate other programs in its PRO-XTEN platform, with 7 preclinical T cell engagers advancing toward candidate selection.

Key Financials
R&D Expenses
$456 million
SG&A Expenses
$92 million
Net Loss
$438 million
Cash, Cash Equivalents and Investments
$782 million
Milestone and Upfront Payments from Astellas
$1.7 billion
Upfront Cash and Equity from Astellas
$315 million
Equity Investment Price
$10.36 per share
Patient Enrollment in VIR-5500 Phase I
58 patients
Objective Response Rate (ORR) at 3,000+ μg/kg
45%
Disease Control Rate at 3,000+ μg/kg
64%
PSA50 Response Rate at 3,000+ μg/kg
82%
Earnings Call Recording
Other Earnings Calls

Management

Dr. Marianne De Backer M.B.A., M.Sc., Ph.D.
CEO & Director
No Bio Available
Dr. Ann M. Hanly Ph.D.
Executive VP & Chief Technology Officer
No Bio Available
Dr. Jeff Calcagno M.D.
Executive VP & Chief Business Officer
No Bio Available
Dr. Louis J. Picker M.D.
Co-Founder & Scientific Advisor
No Bio Available
Mr. Jason O'Byrne
Executive VP & CFO
No Bio Available
Mr. Brent Sabatini
Senior VP, Principal Accounting Officer & Chief Accounting Officer
No Bio Available
Dr. Jennifer Eileen Towne Ph.D.
Executive VP & Chief Scientific Officer
No Bio Available
Ms. Heather Rowe Armstrong
Vice President of Investor Relations
No Bio Available

Contacts

Address
CALIFORNIA
San Francisco
499 Illinois St Ste 500
Contacts
+14159064324.0
www.vir.bio
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