Verona Pharma PLC
NASDAQ:VRNA

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Verona Pharma PLC
NASDAQ:VRNA
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Price: 86 USD Market Closed
Market Cap: 7.4B USD

Verona Pharma PLC
Investor Relations

Verona Pharma PLC, an ambitious player in the biopharmaceutical arena, is woven into the intricate tapestry of the healthcare industry, focusing its energies on respiratory ailments. Born within the thriving biopharma sector in London, this company has targeted chronic obstructive pulmonary disease (COPD) with its novel therapies, driven by the urgent need to alleviate this global burden. The company's flagship product, ensifentrine, serves as a dual inhibitor of the enzymes phosphodiesterase 3 and 4, aiming to enhance lung function and ease the constriction challenges faced by patients. Through strategic clinical trials and robust scientific inquiry, Verona Pharma seeks not only to innovate in treatment but also to deliver tangible hope for those grappling with chronic respiratory conditions.

Verona Pharma's business model is anchored in advancing its drug development pipeline, propelled by a blend of scientific rigor and strategic partnerships. It capitalizes on patent protection and licensing agreements to secure its financial footing, investing heavily in research to drive value creation. The company earns its revenue predominantly from collaborative agreements with larger pharmaceutical entities, milestone payments, and potential royalties upon successful commercialization of its therapies. Through aligning with other industry giants, Verona Pharma not only financially fortifies its pursuits but also accelerates the dissemination of its therapeutic innovations, ensuring that their beneficial impacts reach as many patients as possible. This harmonized approach with partners places Verona Pharma on a trajectory not just of financial growth but also of achieving its underlying mission – transforming the landscape of respiratory disease management.

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Last Earnings Call
Fiscal Period
Q1 2025
Call Date
Apr 29, 2025
AI Summary
Q1 2025

Revenue Breakthrough: For the first time, Verona Pharma reported quarterly revenue exceeding operating expenses (excluding noncash charges), driven by a strong U.S. launch of Ohtuvayre.

Ohtuvayre Sales Surge: Net product sales of Ohtuvayre nearly doubled quarter-over-quarter to $71.3 million, with total net revenue reaching $76.3 million.

Prescription Growth: Filled prescriptions climbed to around 25,000 in Q1, and the number of prescribers rose about 50% to approximately 5,300.

Refill & Persistency Strength: Refills represented 60% of dispenses, and early persistency and refill rates are described as very encouraging.

Gross to Net Improvement: Gross to net discounts improved to "well below 20%" in Q1, better than the previously estimated 25%.

Financial Position: Cash and equivalents were $401.4 million at quarter end; the debt facility was increased to $450 million, providing $200 million in available potential future draws.

Pipeline & Global Progress: Clinical programs advanced, including a planned Phase IIb trial and ongoing studies in bronchiectasis. Ohtuvayre received its first approval outside the U.S., in Macau.

Profitability Outlook: Management expressed confidence in maintaining revenue above cash expenses going forward, with expectations for continued substantial growth.

Key Financials
Ohtuvayre Net Product Sales
$71.3 million
Total Net Revenue
$76.3 million
Prescriptions Filled
Approximately 25,000
Refill Rate
60% of all dispenses
Total Prescribers
Approximately 5,300
Operating Expenses
$86.6 million
Operating Loss
$10.3 million
Net Loss After Tax
$16.3 million
Adjusted Net Income
$20.5 million
Cash and Equivalents
$401.4 million
Share-Based Compensation
$36.8 million
Research and Development Expenses
$14.1 million
Selling, General and Administrative Expenses
$69.1 million
Cost of Ohtuvayre Sales
$3.4 million
Debt Facility Size
$450 million
Outstanding Debt
$250 million
Available Potential Future Draws (Debt Facility)
$200 million
Earnings Call Recording
Other Earnings Calls

Management

Dr. David S. Zaccardelli Pharm.D.
President, CEO & Executive Director
No Bio Available
Mr. Mark W. Hahn
Chief Financial Officer
No Bio Available
Dr. Kathleen A. Rickard M.D.
Chief Medical Officer
No Bio Available
Mr. Andrew Fisher
General Counsel
No Bio Available
Ms. Victoria Stewart
Director of Communications
No Bio Available
Mr. Matthew Casbon
VP of Sales, Marketing & Training
No Bio Available
Ms. Ostra Jewell
Senior Vice President of Human Resources
No Bio Available
Dr. Tara Rheault M.P.H., Ph.D.
Chief Development Officer
No Bio Available
Mr. Christopher Martin
Chief Commercial Officer
No Bio Available
Ms. Caroline Diaz
Senior Vice President of Regulatory Affairs
No Bio Available

Contacts

Address
London
Riverside, 3 More London Place
Contacts
+114402032834200.0
www.veronapharma.com