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Upstream Bio Inc
NASDAQ:UPB

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Upstream Bio Inc
NASDAQ:UPB
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Price: 9.4 USD 2.4% Market Closed
Market Cap: $511.5m

EV/IC

18
Current
1%
Cheaper
vs 3-y average of 18.2

Enterprise Value to Invested Capital (EV/IC) ratio compares a company`s total enterprise value to the capital invested in its business. It shows how efficiently the company`s market value reflects the funds used to generate returns.

EV/IC
18
=
Enterprise Value
$173.8m
/
Invested Capital
$9.5m

Enterprise Value to Invested Capital (EV/IC) ratio compares a company`s total enterprise value to the capital invested in its business. It shows how efficiently the company`s market value reflects the funds used to generate returns.

EV/IC
18
=
Enterprise Value
$173.8m
/
Invested Capital
$9.5m

Valuation Scenarios

Upstream Bio Inc is trading below its 3-year average

If EV/IC returns to its 3-Year Average (18.2), the stock would be worth $9.5 (1% upside from current price).

Statistics
Positive Scenarios
2/4
Maximum Downside
-92%
Maximum Upside
+1%
Average Downside
38%
Scenario EV/IC Value Implied Price Upside/Downside
Current Multiple 18 $9.4
0%
3-Year Average 18.2 $9.5
+1%
5-Year Average 18.2 $9.5
+1%
Industry Average 6.9 $3.59
-62%
Country Average 1.5 $0.78
-92%

Forward EV/IC
Today’s price vs future invested capital

Not enough data available to calculate forward EV/IC

Peer Comparison

All Multiples
EV/IC
P/E
All Countries
Close
Market Cap EV/IC P/E
US
Upstream Bio Inc
NASDAQ:UPB
509.8m USD 18 -3.6
FR
Pharnext SCA
OTC:PNEXF
6T USD -1 260 263.1 -160 127.7
US
Abbvie Inc
NYSE:ABBV
373.6B USD 4.5 87.3
US
Amgen Inc
NASDAQ:AMGN
186.6B USD 3.6 23
US
Gilead Sciences Inc
NASDAQ:GILD
162.4B USD 3.7 19.2
US
Epizyme Inc
F:EPE
94.1B EUR 966.7 -533.6
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
108.6B USD 7.3 27.2
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
74.7B USD 5.6 16.5
NL
argenx SE
XBRU:ARGX
41.3B EUR 14.8 37.4
US
Seagen Inc
F:SGT
39.3B EUR 20.8 -61.8
AU
CSL Ltd
ASX:CSL
60B AUD 1.5 29.5
P/E Multiple
Earnings Growth PEG
US
Upstream Bio Inc
NASDAQ:UPB
Average P/E: 34.3
Negative Multiple: -3.6
N/A N/A
FR
Pharnext SCA
OTC:PNEXF
Negative Multiple: -160 127.7 N/A N/A
US
Abbvie Inc
NYSE:ABBV
87.3
97%
0.9
US
Amgen Inc
NASDAQ:AMGN
23
20%
1.2
US
Gilead Sciences Inc
NASDAQ:GILD
19.2
16%
1.2
US
E
Epizyme Inc
F:EPE
Negative Multiple: -533.6 N/A N/A
US
Vertex Pharmaceuticals Inc
NASDAQ:VRTX
27.2
19%
1.4
US
Regeneron Pharmaceuticals Inc
NASDAQ:REGN
16.5
14%
1.2
NL
argenx SE
XBRU:ARGX
37.4
30%
1.2
US
S
Seagen Inc
F:SGT
Negative Multiple: -61.8 N/A N/A
AU
CSL Ltd
ASX:CSL
29.5
9%
3.3

Market Distribution

Higher than 95% of companies in the United States of America
Percentile
95th
Based on 11 657 companies
95th percentile
18
Low
0 — 0.9
Typical Range
0.9 — 2.9
High
2.9 —
Distribution Statistics
the United States of America
Min 0
30th Percentile 0.9
Median 1.5
70th Percentile 2.9
Max 566 432.7

Upstream Bio Inc
Glance View

Market Cap
511.5m USD
Industry
Biotechnology

Upstream Bio, Inc. is a clinical-stage biotechnology company, which engages in the development of treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. The company is headquartered in Waltham, Massachusetts and currently employs 52 full-time employees. The company went IPO on 2024-10-11. The firm is developing verekitug, the only known antagonist in development that targets the receptor for thymic stromal lymphopoietin (TSLP), a cytokine which is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune mediated diseases. TSLP is a member of a class of epithelial cytokines, also including IL-25 and IL-33, referred to as alarmins. TSLP is primarily produced by epithelial cells, especially in the lung, gastrointestinal tract and skin. The firm has advanced this highly potent monoclonal antibody into separate Phase II trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) and plans to initiate development of chronic obstructive pulmonary disease (COPD).

UPB Intrinsic Value
0.62 USD
Overvaluation 93%
Intrinsic Value
Price $9.4
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