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Clearside Biomedical Inc
NASDAQ:CLSD

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Clearside Biomedical Inc
NASDAQ:CLSD
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Price: 0.41 USD -26.96% Market Closed
Market Cap: $2.1m

EV/EBITDA

0.3
Current
107%
Cheaper
vs 3-y average of -5

Enterprise Value to EBITDA (EV/EBITDA) ratio compares a company`s total enterprise value to its earnings before interest, taxes, depreciation, and amortization. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBITDA
0.3
=
Enterprise Value
$-4.7m
/
EBITDA
$-21.5m

Enterprise Value to EBITDA (EV/EBITDA) ratio compares a company`s total enterprise value to its earnings before interest, taxes, depreciation, and amortization. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBITDA
0.3
=
Enterprise Value
$-4.7m
/
EBITDA
$-21.5m

Valuation Scenarios

Clearside Biomedical Inc is trading below its industry average

If EV/EBITDA returns to its Industry Average (10.1), the stock would be worth $12.3 (2 900% upside from current price).

Statistics
Positive Scenarios
2/2
Maximum Downside
No Downside Scenarios
Maximum Upside
+4 174%
Average Upside
3 537%
Scenario EV/EBITDA Value Implied Price Upside/Downside
Current Multiple 0.3 $0.41
0%
Industry Average 10.1 $12.3
+2 900%
Country Average 14.4 $17.52
+4 174%

Forward EV/EBITDA
Today’s price vs future ebitda

Today's Enterprise Value EBITDA Forward EV/EBITDA
$-4.7m
/
Jul 2025
$-21.5m
=
0.3
Current
$-4.7m
/
Dec 2025
$-17.7m
=
0.3
Forward
$-4.7m
/
Dec 2026
$-7.4m
=
0.6
Forward
$-4.7m
/
Dec 2027
$-11m
=
0.4
Forward

Forward EV/EBITDA shows whether today’s EV/EBITDA still looks high or low once future ebitda are taken into account.

Peer Comparison

All Multiples
EV/EBITDA
P/E
All Countries
Close
Market Cap EV/EBITDA P/E
US
Clearside Biomedical Inc
NASDAQ:CLSD
2.1m USD 0.3 -0.2
US
Eli Lilly and Co
NYSE:LLY
869.1B USD 28.5 42.1
US
Johnson & Johnson
NYSE:JNJ
555.5B USD 16.9 26.4
CH
Roche Holding AG
SIX:ROG
248.4B CHF 11.7 19.8
UK
AstraZeneca PLC
LSE:AZN
231.9B GBP 16.5 29.9
US
Merck & Co Inc
NYSE:MRK
289.8B USD 9.9 15.9
CH
Novartis AG
SIX:NOVN
226.8B CHF 12.5 20.2
IE
Endo International PLC
LSE:0Y5F
244.4B USD 386.8 -83.6
DK
Novo Nordisk A/S
CSE:NOVO B
1.1T DKK 8.3 11.2
US
Pfizer Inc
NYSE:PFE
156.5B USD 7.7 20.1
US
Bristol-Myers Squibb Co
NYSE:BMY
119B USD 7.1 16.9
EV/EBITDA Multiple
EBITDA Growth EV/EBITDA to Growth
US
Clearside Biomedical Inc
NASDAQ:CLSD
Average EV/EBITDA: 46
0.3
N/A N/A
US
Eli Lilly and Co
NYSE:LLY
28.5
21%
1.4
US
Johnson & Johnson
NYSE:JNJ
16.9
8%
2.1
CH
Roche Holding AG
SIX:ROG
11.7
6%
2
UK
AstraZeneca PLC
LSE:AZN
16.5
12%
1.4
US
Merck & Co Inc
NYSE:MRK
9.9
4%
2.5
CH
Novartis AG
SIX:NOVN
12.5
5%
2.5
IE
E
Endo International PLC
LSE:0Y5F
386.8
N/A N/A
DK
Novo Nordisk A/S
CSE:NOVO B
8.3
2%
4.1
US
Pfizer Inc
NYSE:PFE
7.7
-8%
N/A
US
Bristol-Myers Squibb Co
NYSE:BMY
7.1
-10%
N/A
P/E Multiple
Earnings Growth PEG
US
Clearside Biomedical Inc
NASDAQ:CLSD
Average P/E: 22.5
Negative Multiple: -0.2
N/A N/A
US
Eli Lilly and Co
NYSE:LLY
42.1
32%
1.3
US
Johnson & Johnson
NYSE:JNJ
26.4
8%
3.3
CH
Roche Holding AG
SIX:ROG
19.8
14%
1.4
UK
AstraZeneca PLC
LSE:AZN
29.9
25%
1.2
US
Merck & Co Inc
NYSE:MRK
15.9
14%
1.1
CH
Novartis AG
SIX:NOVN
20.2
14%
1.4
IE
E
Endo International PLC
LSE:0Y5F
Negative Multiple: -83.6 N/A N/A
DK
Novo Nordisk A/S
CSE:NOVO B
11.2
0%
N/A
US
Pfizer Inc
NYSE:PFE
20.1
22%
0.9
US
Bristol-Myers Squibb Co
NYSE:BMY
16.9
16%
1.1

Market Distribution

Lower than 99% of companies in the United States of America
Percentile
1st
Based on 9 875 companies
1st percentile
0.3
Low
0 — 10
Typical Range
10 — 21.5
High
21.5 —
Distribution Statistics
the United States of America
Min 0
30th Percentile 10
Median 14.4
70th Percentile 21.5
Max 1 767 274.1

Clearside Biomedical Inc
Glance View

Market Cap
2.1m USD
Industry
Pharmaceuticals

Clearside Biomedical, Inc. is a biopharmaceutical company, which engages in the development of drug therapies to treat blinding diseases of the eye. The company is headquartered in Alpharetta, Georgia and currently employs 34 full-time employees. The company went IPO on 2016-06-02. The firm is focused on developing and delivering therapies to the back of the eye diseases through the suprachoroidal space (SCS). Its SCS injection platform utilizing its SCS Microinjector, enables an in-office, repeatable, non-surgical procedure for the targeted delivery of a variety of therapies to the macula, retina or choroid to preserve and improve vision in patients with sight-threatening eye diseases. The company is focused on developing its own pipeline of small molecule product candidates for administration via its SCS Microinjector, and it also partners with companies developing other ophthalmic therapeutics to be administered using its SCS injection platform. Its lead product candidate, XIPERE, is a preservative-free suspension of the corticosteroid triamcinolone acetonide (TA), formulated for administration through suprachoroidal injection. Its pipeline includes CLS-AX, CLS-301 and Gene Therapy.

CLSD Intrinsic Value
2.84 USD
Undervaluation 86%
Intrinsic Value
Price $0.41
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