Ono Pharmaceutical Co Ltd
TSE:4528

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Ono Pharmaceutical Co Ltd Logo
Ono Pharmaceutical Co Ltd
TSE:4528
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Price: 2 411.5 JPY 1.26% Market Closed
Market Cap: ¥1.2T

Operating Margin

11.1%
Current
Declining
by 14%
vs 3-y average of 25.1%

Operating Margin shows how much profit a company makes from its regular business activities after covering operating costs. It helps measure how efficiently the company turns sales into profit.

Operating Margin
11.1%
=
Operating Income
¥55.9B
/
Revenue
¥503.7B

Operating Margin shows how much profit a company makes from its regular business activities after covering operating costs. It helps measure how efficiently the company turns sales into profit.

Operating Margin
11.1%
=
Operating Income
¥55.9B
/
Revenue
¥503.7B

Peer Comparison

Country Company Market Cap Operating
Margin
JP
Ono Pharmaceutical Co Ltd
TSE:4528
1.1T JPY
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US
Eli Lilly and Co
NYSE:LLY
947.4B USD
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US
Johnson & Johnson
NYSE:JNJ
564B USD
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CH
Roche Holding AG
SIX:ROG
282B CHF
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UK
AstraZeneca PLC
LSE:AZN
214.9B GBP
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US
Merck & Co Inc
NYSE:MRK
290.3B USD
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CH
Novartis AG
SIX:NOVN
225.6B CHF
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DK
Novo Nordisk A/S
CSE:NOVO B
1.6T DKK
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IE
Endo International PLC
LSE:0Y5F
218B USD
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US
Pfizer Inc
NYSE:PFE
145.7B USD
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FR
Sanofi SA
PAR:SAN
98B EUR
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Market Distribution

Higher than 72% of companies in Japan
Percentile
72st
Based on 6 730 companies
72st percentile
11.1%
Low
-125 500% — 4.2%
Typical Range
4.2% — 10.6%
High
10.6% — 9 743.7%
Distribution Statistics
Japan
Min -125 500%
30th Percentile 4.2%
Median 7%
70th Percentile 10.6%
Max 9 743.7%

Ono Pharmaceutical Co Ltd
Glance View

Market Cap
1.2T JPY
Industry
Pharmaceuticals

In the bustling city of Osaka, Japan, Ono Pharmaceutical Co., Ltd. stands as a venerable institution with roots tracing back over three centuries. Origination in 1717 as an apothecary, Ono has evolved into a leading biopharmaceutical company renowned for its pioneering work in immunology. They have a rich history of innovation in drug development, marked by the success of their groundbreaking anti-cancer agent, Opdivo. This is a product of their intensive research and development in the field of immune checkpoint inhibitors, a class of drugs that revolutionizes cancer treatment by bolstering the body's natural defenses to combat malignant cells. Ono’s commitment to R&D, underscored by substantial investment, remains its cornerstone, transforming complex scientific concepts into therapeutic products. The essence of Ono Pharmaceutical’s business model rests on its adeptness at translating scientific excellence into commercial success. They operate within two primary segments: pharmaceutical products and clinical testing-related services. The pharmaceutical segment, the larger of the two, is the engine driving revenue through the development and global distribution of prescription drugs, focusing extensively on treatments in the central nervous system, cancer, and infectious diseases. Ono leverages strategic alliances with global pharmaceutical giants, facilitating broader distribution networks and shared research endeavors, thus amplifying their market presence and financial returns. Their strategy encapsulates a cycle of discovery, development, and commercialization, continually striving to deliver innovative medicinal solutions that enhance the quality of life worldwide.

Intrinsic Value
2 004.84 JPY
Overvaluation 17%
Intrinsic Value
Price
What is Operating Margin?
Operating Margin shows how much profit a company makes from its regular business activities after covering operating costs. It helps measure how efficiently the company turns sales into profit.
How is Operating Margin calculated?

Operating Margin is calculated by dividing the Operating Income by the Revenue.

Operating Margin
11.1%
=
Operating Income
¥55.9B
/
Revenue
¥503.7B
What is Ono Pharmaceutical Co Ltd's current Operating Margin?

The current Operating Margin for Ono Pharmaceutical Co Ltd is 11.1%, which is below its 3-year median of 25.1%.

How has Operating Margin changed over time?

Over the last 3 years, Ono Pharmaceutical Co Ltd’s Operating Margin has decreased from 31% to 11.1%. During this period, it reached a low of 10.3% on Jun 30, 2025 and a high of 33.5% on Mar 31, 2023.

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