Insmed Inc
NASDAQ:INSM

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Insmed Inc
NASDAQ:INSM
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Price: 168.08 USD -5.1% Market Closed
Market Cap: 35.8B USD

Insmed Inc
Investor Relations

Insmed Inc., a biopharmaceutical company rooted in Bridgewater, New Jersey, emerged from the desire to tackle serious and rare diseases with potentially groundbreaking therapies. The company's journey is defined by its commitment to developing novel treatments for patients suffering from conditions often overlooked by mainstream pharmaceutical firms. At the heart of Insmed's operations lies its pursuit of treatments for rare pulmonary diseases, with its flagship product, ARIKAYCE, exemplifying their mission in action. Approved by the FDA for treating Mycobacterium avium complex (MAC) lung disease, ARIKAYCE represents a significant breakthrough, addressing a critical unmet medical need. By targeting specific patient populations with limited options, Insmed taps into niche markets where they face less competition and, simultaneously, a profound opportunity to make a meaningful impact on patient lives.

The company's strategy revolves around leveraging innovative science to build a pipeline rich with potential treatments across various stages of clinical development. It focuses on expanding the use of ARIKAYCE, while also exploring new formulations and indications. Insmed channels resources into research and development, securing patent protections and establishing a robust global presence to ensure its therapies reach the patients who need them. Revenues are primarily generated through product sales, with ARIKAYCE as the cornerstone, alongside strategic partnerships and collaborations that allow for shared expertise and resources. This business model positions Insmed not only as a healthcare provider but as a key player in the biopharmaceutical industry, striving to transform lives by bringing forth meaningful medical innovations.

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Last Earnings Call
Fiscal Period
Q3 2025
Call Date
Oct 30, 2025
AI Summary
Q3 2025

BRINSUPRI Launch: BRINSUPRI achieved $28 million in net sales in its first 6 weeks on the market, with broad early adoption among physicians and positive patient and payer feedback.

ARIKAYCE Strength: ARIKAYCE posted its largest-ever quarterly revenue, up 22% YoY, driven by double-digit growth in all geographies.

Raised Guidance: Full-year 2025 ARIKAYCE revenue guidance was raised to $420–430 million from $405–425 million, reflecting 15–18% projected growth over 2024.

Pipeline Momentum: Multiple late-stage and early-stage programs are progressing, with several major clinical readouts and Phase III trial initiations expected in 2026.

Strong Cash Position: Insmed ended the quarter with approximately $1.7 billion in cash and marketable securities, supporting further launches and R&D.

Early Launch Caveats: Management cautioned that BRINSUPRI’s early results include inventory stocking; Q4 will provide a clearer view of underlying demand.

Market Access: Broad payer coverage for BRINSUPRI has been achieved so far, but final access criteria are still being established.

Key Financials
BRINSUPRI Net Sales
$28 million
BRINSUPRI New Patients (Q3)
2,550
BRINSUPRI Prescribing Physicians (Q3)
1,700
ARIKAYCE Quarterly Revenue
Largest quarter ever
ARIKAYCE FY25 Revenue Guidance
$420–430 million
ARIKAYCE FY25 Revenue Growth vs 2024
15% to 18%
Cash, Cash Equivalents and Marketable Securities
$1.7 billion
Cost of Product Revenues
$29.4 million
Cost of Product Revenues as % of Revenue
20.6%
Earnings Call Recording
Other Earnings Calls

Management

Mr. William H. Lewis J.D., M.B.A.
President, CEO & Chairman
No Bio Available
Ms. Sara M. Bonstein M.B.A.
Chief Financial Officer
No Bio Available
Mr. John Drayton Wise M.B.A.
Chief Commercial Officer
No Bio Available
Mr. Brian K. Kaspar Ph.D.
Chief Scientific Officer
No Bio Available
Ms. Eleanor Barisser
Associate Director of Investor Relations
No Bio Available
Mandy Fahey
Executive Director of Corporate Communications
No Bio Available
Mr. Neil Hughes
GM & Head of Europe, Middle East and Africa
No Bio Available
Dr. Kevin Mange M.D.
Head of Clinical Development
No Bio Available
Dr. Paul D. Streck M.D.
Advisor
No Bio Available

Contacts

Address
NEW JERSEY
Bridgewater
700 Us Highway 202/206
Contacts
+19089779900.0
insmed.com