Autolus Therapeutics PLC
NASDAQ:AUTL

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Autolus Therapeutics PLC Logo
Autolus Therapeutics PLC
NASDAQ:AUTL
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Price: 1.61 USD 1.26% Market Closed
Market Cap: 428.5m USD

Autolus Therapeutics PLC
Investor Relations

Autolus Therapeutics Plc is a biopharmaceutical company, which engages in the development and commercialization of gene therapies. The firm is focused on developing programmed T cell therapies for the treatment of cancer. The firm has a pipeline of product candidates in development for the treatment of hematological malignancies and solid tumors. Its lead clinical programs include AUTO1 (obecabtagene autoleucel, Obe-Cel), AUTO4, and AUTO6 / AUTO6NG. Obe-cel is a CD19 CAR T cell investigational therapy designed to overcome limitations in clinical activity and safety. Obe-cel reduces toxicity and is less prone to T cell exhaustion, which could improve persistence and the ability of programmed T cells to engage in serial killing of target cancer cells. AUTO4 is a T cell therapy for the treatment of peripheral T-cell lymphoma targeting TRBC1. AUTO6 / AUTO6NG is a T cell therapy targeting GD2 in development for the treatment of neuroblastoma. Its other clinical programs include AUTO5, AUTO7, and AUTO8.

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Last Earnings Call
Fiscal Period
Q3 2025
Call Date
Nov 12, 2025
AI Summary
Q3 2025

Net Sales: AUCATZYL achieved $21.1 million in net product revenue for Q3 2025, up slightly from $20.9 million in Q2.

Market Leadership: Autolus gained market leadership in relapsed/refractory B-ALL in its first 9 months on the US market, with broad access and reliable delivery.

Deferred Revenue: Deferred revenue at quarter-end was $7.6 million, a significant increase from $2.1 million in Q2, indicating products delivered but not yet infused.

Cost of Sales & Margins: Cost of sales was $28.6 million, with management expecting improvements as volumes rise and operational efficiency increases.

Pipeline Progress: Multiple expansion studies underway, including pivotal trials in pediatric ALL and lupus nephritis, and an exploratory study in progressive multiple sclerosis.

Cash Position: Ended Q3 with $367.4 million in cash and equivalents, expected to fund ongoing launches and pivotal trials.

Operational Stability: Manufacturing success rate above 90%, and coverage for over 90% of US covered lives.

Key Financials
Net Product Revenue
$21.1 million
Deferred Revenue
$7.6 million
Net Sales (9 months ended Sep 30)
$51 million
Cost of Sales
$28.6 million
Research and Development Expense
$27.9 million
Selling, General and Administrative Expense
$36.3 million
Loss from Operations
$71.6 million
Net Loss
$79.1 million
Cash, Cash Equivalents, and Marketable Securities
$367.4 million
Manufacturing Success Rate
above 90%
Patient Access (US covered lives)
more than 90%
Authorized Centers (US)
60 centers
Earnings Call Recording
Other Earnings Calls

Management

Dr. Christian Martin Itin Ph.D.
CEO & Director
No Bio Available
Dr. Martin Pule M.D., MBBS
Founder, Senior VP & Chief Scientific Officer
No Bio Available
Mr. Robert F. Dolski
Senior VP & CFO
No Bio Available
Mr. Christopher Vann
Senior VP & COO
No Bio Available
Mr. David Brochu
Senior VP & Chief Technical Officer
No Bio Available
Mr. Alexander Swan
Senior VP & Chief Human Resources Officer
No Bio Available
Mr. Brent Rice
Senior VP, Chief Commercial Officer & Site Head of US
No Bio Available
Ms. Olivia Manser
Director of Investor Relations
No Bio Available
Mr. Alex Driggs
Senior VP of Legal Affairs & General Counsel and Secretary
No Bio Available
Dr. Chris Williams
Senior VP & Chief Business Development Officer
No Bio Available

Contacts

Address
London
The Mediaworks, 191 Wood Lane
Contacts
+442038296230.0
www.autolus.com