Trump Administration Secures Major Drug Price Cuts for Popular Weight-Loss Treatments

Nov 6, 2025

President Donald Trump announced major deals with drugmakers Eli Lilly and Novo Nordisk to cut prices for widely-used weight-loss medications. The agreement aims to make these drugs, which include GLP-1-based obesity treatments, significantly more affordable for Americans.

As part of the deal, prices for these weight-loss medications will be lowered by up to 74%. Some patients currently pay over $1,300 per month; with the new agreement, prices may drop to as low as $149 per month for some users.

The lower prices will be available to certain Medicare and Medicaid patients, and consumers who buy through a new government website, TrumpRx.gov, launching in January 2026.

The deal also starts a pilot program for Medicare Part D (the prescription drug benefit for seniors) to cover these obesity drugs, including Eli Lilly’s Zepbound and orforglipron (if approved), which will be offered at $50 per month for eligible beneficiaries.

Novo Nordisk stated that these changes are expected to lower its global sales slightly in 2026, as the company adjusts to the new pricing model in the U.S.

What drugs are included in this price cut?

The agreement covers popular GLP-1-based weight-loss drugs from Eli Lilly and Novo Nordisk, including medications like Zepbound and upcoming oral pills.

Who will benefit from the lower prices?

Lower prices will be available to U.S. Medicare and Medicaid patients, and to anyone who uses the TrumpRx.gov website once it launches.

When do these changes take effect?

The new prices and expanded access are set to begin in January 2026 with the launch of TrumpRx.gov and the Medicare Part D pilot program.

Why are the companies lowering their prices?

The companies made the agreement with the U.S. government to make these important medications more affordable and accessible to more Americans.

Sources
Trump announces deals with Eli Lilly, Novo Nordisk to slash weight loss drug pri...
CNBC
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Market Watch
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CNBC Television
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Reuters
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Benzinga
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PRNewsWire
Medicare beneficiaries with obesity or overweight will have access to Zepbound and orforglipron, if approved, at $50 a month  INDIANAPOLIS , Nov. 6, 2025 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today announced an agreement with the U.S. government to expand access to its obesity medicines...
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Investors Business Daily
The Trump administration announced deals Thursday with Eli Lilly and Novo Nordisk to slash the prices of their weight-loss drugs.
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Invezz
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CNBC
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Proactive Investors
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Yahoo Finance
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Reuters
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Bloomberg Markets and Finance
Eli Lilly & Co. and Novo Nordisk A/S secured deals with the Trump administration to slash prices for their weight-loss drugs in exchange for tariff relief and wider access for Medicare patients. President Trump spoke about the deal earlier today from the Oval Office.
Novo Nordisk shares fall after deal with Trump to slash obesity drug prices
Reuters
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Seeking Alpha
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