Eli Lilly Lowers Price of Zepbound Obesity Drug to Improve Access

Dec 1, 2025

Eli Lilly has announced a price reduction for its obesity drug Zepbound, aiming to make the medication more affordable for U.S. patients. The lower prices apply to single-dose vials available through Lilly’s direct-to-consumer platform, LillyDirect.

Starting December 1, patients paying cash with a valid prescription can buy Zepbound vials for $299 to $449 per month, depending on the dose. Previously, these prices ranged from $349 to $499 per month. The list price of Zepbound before any discounts or rebates was $1,086 per month.

The move comes as demand grows for weight-loss treatments and competition increases among pharmaceutical companies. Shares of Eli Lilly fell slightly following the price announcement.

What is Zepbound?

Zepbound is a prescription drug developed by Eli Lilly for weight loss and obesity treatment.

Who can get the new Zepbound prices?

Patients in the U.S. with a valid prescription who pay cash on LillyDirect are eligible for the new prices.

Why did Eli Lilly lower the price of Zepbound?

The price was lowered to make the drug more affordable and widen access as demand and competition in the weight-loss drug market increase.

Sources
Eli Lilly cuts Zepbound price to widen access for obesity drug
Reuters
Eli Lilly said on Monday it has lowered the price of single-dose vials of its popular obesity drug Zepbound to make the treatment more affordable for U.S. patients, as demand for weight-loss therapies surge.
Eli Lilly cuts cash prices of Zepbound weight loss drug vials on direct-to-consu...
CNBC
Eli Lilly said it is lowering the cash prices of single-dose vials of its blockbuster weight loss drug Zepbound on its direct-to-consumer platform, LillyDirect. Starting Dec. 1, cash-paying patients with a valid prescription can pay $299 to $449 per month for Zepbound vials on LillyDirect, depending...
Lilly Cuts Prices for Cash Buyers of Weight-Loss Drug Zepbound
Bloomberg Markets and Finance
Eli Lilly is cutting prices again for those who pay cash for introductory doses of the weight-loss drug Zepbound. The lowest dose vial will cost $299 a month, that would be a saving of about $50.
Eli Lilly Lowers Weight-Loss Drug Zepbound Prices After Trump Deal
Forbes
$1,086. That's the monthly cost of Zepbound before any discounts or rebates, according to Eli Lilly. The list price for Ozempic is just over $997 per month.
Eli Lilly Stock in Focus After Slashing Cost of Popular Drug
Schaeffers Research
Shares of Eli Lilly and Co (NYSE:LLY) are sliding into the red, down 0.8% to trade at $1,066.96 at last check, amid news the pharma giant cut prices on popular weight loss drug Zepbound.
Eli Lilly cuts price of Zepbound in heightened weight-loss drug competition
Proactive Investors
Eli Lilly and Co (NYSE:LLY) said on Monday it is lowering the cash prices of its weight-loss drug Zepbound, marking the latest move in a growing price battle with rival Novo Nordisk. The US pharmaceutical giant said single-dose vials of Zepbound will now be available on its direct-to-consumer platfo...
Eli Lilly Trims Price of Popular Weight-Loss Drug on Its Site a Month After Trum...
Investopedia
Eli Lilly (LLY) said Monday that it's lowering the price of its popular weight-loss drug Zepbound, about a month after striking a deal with the Trump administration to lower drug costs.
Eli Lilly cuts cash prices of Zepbound weight loss drug vials on direct-to-consu...
CNBC Television
Eli Lilly on Monday said it is lowering the cash prices of single-dose vials of its blockbuster weight loss drug Zepbound on its direct-to-consumer platform, LillyDirect.
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